Original scientific paper
https://doi.org/10.3325/cmj.2021.62.480
Improving breast cancer prediction using a pattern recognition network with optimal feature subsets
Serdar Gündoğdu
orcid.org/0000-0003-2549-5284
; Department of Computer Technologies, Dokuz Eylül University, Izmir, Turkey
Abstract
Aim To predict the presence of breast cancer by using a
pattern recognition network with optimal features based
on routine blood analysis parameters and anthropometric data.
Methods Sensitivity, specificity, accuracy, Matthews correlation coefficient (MCC), and Fowlkes-Mallows (FM) index of each model were calculated. Glucose, insulin, age,
homeostatic model assessment, leptin, body mass index
(BMI), resistin, adiponectin, and monocyte chemoattractant protein-1 were used as predictors.
Results Pattern recognition network distinguished patients with breast cancer disease from healthy people. The
best classification performance was obtained by using BMI,
age, glucose, resistin, and adiponectin, and in a model with
two hidden layers with 11 and 100 neurons in the neural
network. The accuracy, sensitivity, specificity, FM index, and
MCC values of the best model were 94.1%, 100%, 88.9%,
94.3%, and 88.9%, respectively.
Conclusion Breast cancer diagnosis was successfully predicted using only five features. A model using a pattern
recognition network with optimal feature subsets proposed in this study could be used to improve the early detection of breast cancer.
Keywords
Hrčak ID:
278472
URI
Publication date:
21.10.2021.
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