Professional paper

https://doi.org/10.20471/acc.2022.61.02.21

Characteristics of Chronic Rhinosinusitis Phenotypes in Patients Undergoing Functional Endoscopic Sinus Surgery: an Observational Cohort Retrospective Study

Martina Radetić ; Alba Rubra Polyclinic, Zagreb, Croatia
Jeffry Mattar ; School of Medicine, University of Zagreb, Zagreb, Croatia
Andro Košec ; School of Medicine, University of Zagreb, Zagreb, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Filip Bacan ; School of Medicine, University of Zagreb, Zagreb, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Tomislav Baudoin ; School of Medicine, University of Zagreb, Zagreb, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia

Abstract

This study analyzed the characteristics of chronic rhinosinusitis patients with and
without nasal polyps failing conservative treatment and undergoing functional endoscopic sinus surgery
as part of their treatment for chronic inflammatory sinonasal disease. The aim of this retrospective
single-institution cohort study conducted at a university hospital tertiary referral center was to evaluate
the characteristics of patients with both disease phenotypes in whom conservative treatment was unsuccessful.
Patients who were surgically treated with functional endoscopic sinus surgery performed by two
rhinology surgeons during a one-year period (2016) were enrolled in the study. Patient data collection
included demographics, risk factor exposure, diagnosis, and type of endoscopic surgical procedure performed.
In total, 185 patients were included in the study. Patients with malignant disease and those with
incomplete data were excluded from the study. In the group of patients with nasal polyps, mean age, male
gender, presence of allergy (34.9%), asthma (21.4%), aspirin sensitivity (6.3%), cystic fibrosis (1.6%), and
previous nasal surgery rates (36.5%) were significantly higher as compared with the group of patients
with chronic rhinosinusitis without nasal polyps. Septal deviation was more prevalent in the chronic
rhinosinusitis group (55%) as compared to the group with nasal polyps (25%). The ethmoid (17%) and
maxillary sinus (13%) were most frequently involved, but most of the patients who needed surgery had
involvement of multiple or all sinuses (40%). The reasons for conservative treatment failure in chronic
rhinosinusitis are multifactorial, but identifying the most prevalent characteristics in patients treated
surgically may be helpful in identifying patients who would benefit most from surgery.

Keywords

Chronic rhinosinusitis; Nasal polyps; Functional endoscopic sinus surgery; Patient characteristics

Hrčak ID:

285014

URI

https://hrcak.srce.hr/285014

Publication date:

1.8.2022.

Article data in other languages: croatian

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