Original scientific paper
https://doi.org/https://doi.org/10.5599/jese.3446
Highly sensitive and selective electrochemical determination of ciprofloxacin using modified screen-printed electrode
Hassan Ali M. Jawad
; College of Pharmacy, Alfarahdi University, Baghdad, Iraq
Abstract
In this study, the Zn-based zeolitic imidazole framework-L (ZIF-L)/graphene oxide
(ZIF-L(Zn)/GO) nanocomposite was prepared and used for ciprofloxacin detection. To detect ciprofloxacin (CFN), the nanocomposite was used to alter the screen-printed electrode' surface (ZIF-L(Zn)/GO/SPE). With a low limit of detection of 0.01 μM, good sensitivity of 0.1493 μA μM-1, and a linear dependence between the current response and CFN concentration over the range of 0.05 to 300.0 μM, the sensor exhibited electrocatalytic behaviour toward CFN in phosphate buffer solution. Additionally, by identifying CFN in actual samples, the manufactured sensor's usefulness was shown.
Keywords
Antibiotic determination; voltametric sensor; modified electrode; graphene oxide composite; zeolitic imidazolate framework; antibiotics determination
Hrčak ID:
351281
URI
Publication date:
8.7.2026.
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