Original scientific paper
Pain Relieve after Impacted Wisdom Teeth Extraction Dependent on the Drug Therapy
Edin Selimović
Lejla Ibrahimagić-Šeper
Nikola Petričević
Petra Nola-Fuchs
Abstract
Purpose of this study was to compare the effects of combined therapy using nonsteroid anti-inflammatory analgetics
and corticosteroids, and the effects of the mono-therapy with same drugs for post-operative pain after surgical removal of
the impacted mandibular third molar. The study was completed at the Department of Oral Surgery and at the Department
of Dental Medicine of the Public Institute Health Center Zenica in Zenica. The research included 60 patients divided into
3 groups using random selection, including both sexes. Age range was between 18 and 45 years. All participants came
without any pain or other inflammatory symptoms at the time of oral surgical intervention. Two medicaments were prescribed
after the impacted tooth removal: 15 mg of nonsteroid anti-inflammatory analgesic drug (Meloxicam, Bosnalijek,
BiH) and 32 mg Methylprednisolone (corticosteroid, Bosnalijek, BiH). Both medicaments were applied per os, according
to schedule determined by the research protocol. The level of post-surgical pain was evaluated by the 1–10 visual
analog scale (VAS). One way ANOVA was made with Tuckey post-hoc tests. Statistically significant difference (p<0.05)
was found between the group treated with mono therapy and the group treated with combined therapy. Application of
mono therapy using only corticosteroids or only nonsteroid anti-inflammatory pain-killers was less effective compared to
the combined therapy with both medicaments after surgical removal of the impacted mandibular third molar.
Keywords
impacted third molars; pain; analgesic drug (pain-killers); corticosteroids
Hrčak ID:
64761
URI
Publication date:
7.3.2011.
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