Recenzija, Prikaz slučaja

https://doi.org/10.20471/acc.2021.60.02.21

Spontaneous Resolution of a Nonfunctioning Pituitary Adenoma over One-Month Period: a Case Report

Luka Komić orcid.org/0000-0002-0616-9101 ; University of Split, School of Medicine, Split, Croatia
Ivan Kruljac ; Mladen Sekso Department of Endocrinology, Diabetes and Metabolic Diseases, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Gorana Mirošević ; Mladen Sekso Department of Endocrinology, Diabetes and Metabolic Diseases, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Petar Gaćina ; Department of Internal Medicine, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; University of Zagreb, School of Dental Medicine, Zagreb, Croatia
Hrvoje Ivan Pećina ; Department of Radiology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Vatroslav Čerina ; Department of Neurosurgery, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Domagoj Gajski orcid.org/0000-0002-2517-5726 ; University of Zagreb, School of Dental Medicine, Zagreb, Croatia; Department of Neurosurgery, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; University of Applied Health Sciences, Zagreb, Croatia
Kristina Blaslov ; Mladen Sekso Department of Endocrinology, Diabetes and Metabolic Diseases, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Krešimir Rotim ; Department of Neurosurgery, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; University of Applied Health Sciences, Zagreb, Croatia; Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, Osijek, Croatia
Miljan Vrkljan ; Mladen Sekso Department of Endocrinology, Diabetes and Metabolic Diseases, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia

Sažetak

Spontaneous resolution of nonfunctioning pituitary adenoma after hemorrhagic
apoplexy is a rare clinical entity of unknown etiology and is defined as disappearance of a tumor without
any specific treatment. Here we present a 54-year-old male patient who presented with acute
onset of severe headache, vomiting, photophobia, and sonophobia. He was referred to brain computed
tomography, which showed a 16x12x16 mm tumor mass located in the sellar region with signs of
hemorrhage. Endocrinologic evaluation was consistent with under-function of pituitary gonadotropic
cells. Magnetic resonance imaging (MRI) performed ten days later was consistent with hemorrhagic
apoplexy of the pituitary adenoma. The patient’s symptoms resolved after conservative treatment with
dexamethasone, but he was scheduled for elective pituitary surgery. Preoperative MRI was performed
one month after the first one and disclosed normal pituitary gland without any signs of adenoma. Our
case is remarkable due to the fact that spontaneous remission of pituitary adenoma occurred within
the first month, which is the shortest interval reported to date. Our case highlights the importance of
conservative therapy as the first-line treatment for pituitary apoplexy in the absence of neurological
impairment, since spontaneous remission may occur in a short time interval.

Ključne riječi

Pituitary neoplasms; Pituitary apoplexy; Adenoma; Empty sella syndrome; Neoplasm regression, spontaneous; Remission, spontaneous

Hrčak ID:

263808

URI

https://hrcak.srce.hr/263808

Datum izdavanja:

1.6.2021.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.413 *