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Journal of Electrochemical Science and Engineering, Vol. 16 , 2026.

Izvorni znanstveni članak

https://doi.org/10.5599/jese.2978

Ultrasensitive and selective electrochemical sensor for paracetamol based on thiacloprid nanocomposite

Khairol Harmi Mohamad Shukari ; Department of Chemistry, Faculty of Science and Mathematics, Sultan Idris Education University, 35900 Tanjong Malim, Perak, Malaysia
Mohamad Syahrizal Ahmad orcid id orcid.org/0000-0002-9278-6332 ; Department of Chemistry, Faculty of Science and Mathematics, Sultan Idris Education University, 35900 Tanjong Malim, Perak, Malaysia *
Illyas Md Isa ; Department of Chemistry, Faculty of Science and Mathematics, Sultan Idris Education University, 35900 Tanjong Malim, Perak, Malaysia
Norhayati Hashim ; Department of Chemistry, Faculty of Science and Mathematics, Sultan Idris Education University, 35900 Tanjong Malim, Perak, Malaysia
Mohamad Idris Saidin orcid id orcid.org/0000-0001-9735-7150 ; Department of Chemistry, Faculty of Science and Mathematics, Sultan Idris Education University, 35900 Tanjong Malim, Perak, Malaysia
Suyanta M. Si ; Department of Chemistry Education, Faculty of Mathematics and Natural Science, Yogyakarta State University, Indonesia
Rahadian Zainul ; Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Padang, West Sumatera 25171, Indonesia
Sofian Ibrahim ; Technical Support Division, Malaysian Nuclear Agency, 43000 Kajang, Malaysia

* Dopisni autor.

Puni tekst: engleski pdf 1.046 Kb

preuzimanja: 87

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Sažetak

The study introduces a novel electrochemical sensor for paracetamol (PCM) determination based on a nanocomposite composed of zinc layered hydroxide (ZLH) intercalated with sodium dodecyl sulphate and thiacloprid (SDS-THI), integrated with multiwalled carbon nano­tubes (MWCNTs). The sensor aims to address limitations of conventional analytical techniques and improve sensitivity, detection limits, and portability. Electrochemical techniques, including electrochemical impedance spectroscopy, square wave voltammetry and cyclic voltammetry, were employed to characterize the sensor performance. The ZLH-SDS-THI/MWCNTs sensor showed superior electrocatalytic activity, with a wide linear range (0.7 to 30 mM) and a low detection limit (LOD = 0.33 mM), outperforming several previously reported sensors. The enhanced performance is attributed to the synergistic properties of the composite materials, which offer improved electron transfer, a high surface area, and effective analyte interaction. Importantly, the sensor demonstrated excellent selectivity, as interference studies revealed that common biological and ionic species such as ascorbic acid, glucose, fructose, lysine, chloride, magnesium, and sulphate ions, even when present at 10-, 20-, and 50-fold excess concentrations relative to PCM, caused less than 10 % signal variation. This confirms the sensor’s robustness and reliability in complex sample matrices. Overall, this work highlights the potential of incorporating unconventional organic dopants, such as thiacloprid, into layered nanostructures to enhance the performance of electrochemical sensors, offering a promising platform for the selective and sensitive determination of pharmaceutical compounds in environmental and clinical applications.

Ključne riječi

Acetaminophen drug; zinc layered hydroxide; organic dopants; multiwalled carbon nanotubes; voltammetry techniques

Hrčak ID:

344854

URI

https://hrcak.srce.hr/344854

Datum izdavanja:

4.11.2025.

Posjeta: 222 *