Izvorni znanstveni članak
A Rare Case of Acquired Ichthyosis Related to Pulmonary Tuberculosis
Chiara Zangrando
; U.O.C. Dermatologia, Parma, Italy
*
Roberto D’Astolto
; Clinica Dermatologica Ospedale Policlinico “SS. Annunziata”, Chieti, Italy
Claudio Feliciani
; University of Parma, Parma, Italy
* Dopisni autor.
Sažetak
Acquired ichthyosis (AI) is a clinical condition associated with keratinization
defects, characterized by accumulation of cutaneous scales, with or without epidermal
proliferation and inflammation of the dermis. With this report, we want to present the
case of a 58-year-old man who referred to our clinic with severe and diffuse scaling of
the skin associated with irrepressible itching, unresponsive to oral antihistamines. After
our diagnosis of acquired ichthyosis, we subjected him to diagnostic investigations
aimed at identifying the triggering cause. After performing laboratory tests and radiographic
investigations, the diagnosis of pulmonary tuberculosis (TBC) emerged. The
treatment of the underlying TBC initially did not improve the patient’s clinical condition,
but after the interruption of treatment with isoniazid, the cutaneous involvement
resolved. In literature, to date, there is poor scientific evidence of tuberculosis-related
and isoniazid-related ichthyosis; moreover, some of those patients had a concomitant
history of solid tumors (long associated with acquired ichthyosis), which makes it more
difficult to identify the triggering cause among many
Ključne riječi
acquired ichthyosis; tuberculosis; pulmonary
Hrčak ID:
346655
URI
Datum izdavanja:
10.4.2025.
Posjeta: 14 *