Recenzija, Prikaz slučaja

https://doi.org/10.20471/acc.2026.65.02.18

Synchronous Renal, Urinary Bladder, Prostatic and Lung Cancer – Case Report With PD-L1 Status and Review

Matej Knežević orcid.org/0009-0002-1017-2407 ; Clinical Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia *
Ivan Franin ; Ljudevit Jurak Clinical Department of Pathology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Borislav Spajić ; Clinical Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia
Igor Tomašković ; Clinical Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; School of Medicine, Croatian Catholic University, Zagreb, Croatia
Igor Grubišić ; Clinical Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Jure Murgić ; Department of Oncology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Boris Ružić ; Clinical Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia
Monika Ulamec ; Ljudevit Jurak Clinical Department of Pathology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia

* Dopisni autor.

Sažetak

Our aim was to report the case of a patient treated for multiple synchronous
primary carcinomas affecting the kidney, urinary bladder, prostate, and lungs.
A 69-year-old man presented with macrohematuria, without any other symptoms.
An initial ultrasound examination and cystoscopy revealed a bladder tumor.
During a computer tomography scan, a left kidney and lung tumor were incidentally
found. The patient underwent transurethral bladder tumor resection,
nephrectomy, pulmonic lobectomy, and finally radical cystectomy due to additional
evidence of invasive bladder cancer. The pathology report after the last
surgery also revealed prostatic cancer. The pathological processing was extended
by immunohistochemical analysis. This report showed a rare synchronous
appearance of four independent carcinomas in one patient, who was surgically
treated. To our knowledge, this is the first case presenting this combination of
tumors.

Ključne riječi

Case report; Multiple primary malignant neoplasms; PD-L1

Hrčak ID:

347732

URI

https://hrcak.srce.hr/347732

Datum izdavanja:

10.6.2026.

Podaci na drugim jezicima: hrvatski

Posjeta: 0 *