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https://doi.org/10.3325/cmj.2025.66.213

Regional anesthesia without opioid administration in mastectomy surgeries followed by breast reconstruction with implants: a randomized controlled study

Domagoj Eljuga ; Libertas International University, Zagreb, Croatia
Rhea Marie Mužar ; Department of Plastic and Reconstructive Surgery, Dubrava University Hospital, Zagreb, Croatia *
Ivo Jurišić ; Department of Anesthesiology, Reanimatology and Intensive Care Medicine, Dubrava University Hospital, Zagreb, Croatia
Jasminka Peršec ; Department of Anesthesiology, Reanimatology and Intensive Care Medicine, Dubrava University Hospital, Zagreb, Croatia
Ksenija Eljuga ; Nursing Department, Bjelovar University of Applied Sciences, Bjelovar, Croatia
Josip Jaman ; Department of Plastic and Reconstructive Surgery, Dubrava University Hospital, Zagreb, Croatia
Željka Roje ; Department of Plastic and Reconstructive Surgery, Dubrava University Hospital, Zagreb, Croatia
Krešimir Martić ; Department of Plastic and Reconstructive Surgery, Dubrava University Hospital, Zagreb, Croatia
Zlatko Vlajčić ; Department of Plastic and Reconstructive Surgery, Dubrava University Hospital, Zagreb, Croatia
Rado Žic ; Department of Plastic and Reconstructive Surgery, Dubrava University Hospital, Zagreb, Croatia

* Dopisni autor.


Puni tekst: engleski pdf 766 Kb

str. 213-219

preuzimanja: 0

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Sažetak

Aim To compare regional anesthesia without opioid ad
ministration following subcutaneous mastectomy and
breast reconstruction with implants in the pre-pectoral
plane with general anesthesia in terms of pain relief, opioid
consumption, and hospital stay duration.
Methods This randomized controlled study enrolled pa
tients who underwent mastectomy with reconstruction
of the breast either with permanent implants or tissue ex
pander placement in the pre-pectoral plane. A total of 40
patients met the inclusion criteria. The regional anesthesia
group (n = 20) received a pectoralis muscle block (PECS I),
thoracic paravertebral block (TPVB), and serratus anterior
muscle plane block (SAP) following a uniform protocol,
and the control group (n = 20) underwent general anes
thesia. Pain was assessed by using the numeric rating scale
(NRS) from 30 minutes after surgery up to ten days post
operatively.
Results NRS pain scores were significantly higher in the
regional anesthesia group, independent of the patients’
physical daily activity level, even up to 10 days after sur
gery. Opioid consumption and length of hospital stay did
not differ significantly.
Conclusion Regional anesthesia using a combination of
a TBVP, PECS I, and SAP has a long-lasting and satisfacto
ry analgesic effect without the introduction of opioids. In
the future, a novel gold standard protocol should be es
tablished that can be offered to every patient undergoing
breast surgery.

Ključne riječi

Hrčak ID:

352491

URI

https://hrcak.srce.hr/352491

Datum izdavanja:

25.6.2025.

Posjeta: 0 *