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GENDER DIFFERENCES IN GLUCOSE BLOOD LEVELS IN RATS AFTER FORCED SWIMMING EXERCISE
Almira Hadžović-Džuvo
; Department of Physiology, Faculty of Medicine, University of Sarajevo, Bosnia and Herzegovina
Eldan Kapur
; Department of Anatomy, Faculty of Medicine, University of Sarajevo, Bosnia and Herzegovina
Amina Valjevac
; Department of Physiology, Faculty of Medicine, University of Sarajevo, Bosnia and Herzegovina
Orhan Lepara
; Department of Physiology, Faculty of Medicine, University of Sarajevo, Bosnia and Herzegovina
Nesina Avdagić
; Department of Physiology, Faculty of Medicine, University of Sarajevo, Bosnia and Herzegovina
Jasmin Alajbegović
; Faculty of Medicine, University of Sarajevo
Sažetak
The aim of this study was to investigate possible
differences in blood glucose levels between male and
female rats immediately after acute bout of forced
swimming exercise. Adult male Wistar rats (weight 300-
350 g) were divided into two groups by gender: males (n
=8) and females (n =8). All the rats were given standard rat
chow and tap water ad libitum and were housed at 25±3o C
on a 12-hour dark/light cycle. Both groups of rats were
exposed to forced swimming stress daily, for 6 days.
Duration of each swimming session progressively
increased from 5 minutes on the first day to 30 minutes on
sixth day, allowing adaptation to swimming conditions.
The rats were forced to swim in plastic tanks (90 cm wide,
120 cm deep) containing tap water (temperature ca. 25
degrees C). The depth of water was 40 cm. Seventh day we
performed acute bout of 40 minutes swimming exercise.
Animals were fasted 12 hours before start of last
swimming sessions to obtain fasting blood glucose levels.
Preexercise blood samples were taken immediately before
last swimming session (7th day) and postexercise samples
immediately after the last swimming session from rat's tail
vein. Glucose levels in blood were determined using
Optium Xceed™ Diabetes Monitoring System (Abbot).
Before last swimming session male rats had slightly lower
glucose levels in comparation with female rats, but this
difference was not statistically significant (3.77vs4.64
mmol/l). Acute bout of forced swimming exercise raised
blood glucose level and established values in postexercise
period were significantly higher in both study group in
comparation to values before exercise. Male rats had
greater postexercise glucose blood levels (11.85 mmol/l)
in comparation with female rats (6.26 mmol/l). Our
findings document the existence of gender impact on the
glucose postexercise concentrations confirming the
differences in the energy substrates utilization and
glucose metabolism regulation during and after exercise.
Ključne riječi
glucose; gender; exercise; rats
Hrčak ID:
78031
URI
Datum izdavanja:
30.12.2011.
Posjeta: 1.919 *