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Histomorphometric Analysis of Subchondral Bone of the Femoral Head in Osteoarthritis and Osteoporosis
Marin Marinović
Edo Bazdulj
Tanja Čelić
Tedi Cicvarić
Dragica Bobinac
Sažetak
There have been reports both supporting and refuting an inverse relationship between hip fracture and hip osteoarthritis
(OA). We have investigated this relationship using histomorphometric study of femoral head subchondral
bone1–5. We studied 74 subjects with hip fracture (74% females) and 24 subjects with osteoarthritis (45% females). By
histomorphometric analysis of parafined sections, we analysed followed subhondral trabecular bone parameters bone
volume(BV), bone volume/tissue volume (BV/TV), trabecular thickness (Tb.Th.), trabecular number (Tb.N.) and trabecular
separation (Tb.S.). The subjects with osteoarthritis and subjects with hip fracture had BV/TV 31.3% and 19.6% respectively.
BV/TV of osteoarthritis group was rather uniform whereas BV/TV of hip fracture group was greatly ranged
and we devided it into three subgroups, 13.2%, 19.8% and 25.9% recpectively. The OA group and hip fracture groups had
Tb.Th. as followed 0.205 mm, 0.148 mm, 0.170 mm and 0.183 mm respectively. The OA group and hip fracture three
subgroups had Tb.N. as followed 1.454/mm, 0.897/mm, 1.170/mm and 1.425/mm respectively. The OA group and hip
fracture three subgroups had Tb.S. as followed 0.518 mm, 0.681 mm, 0.620 mm and 0.550 mm respectively. The results
of our study support an inverse relationship between hip fracture and hip osteoarthritis.
Ključne riječi
cortical plate; microCT; osteoarthritis; osteoporosis; subchondral bone
Hrčak ID:
72218
URI
Datum izdavanja:
25.9.2011.
Posjeta: 1.477 *