Skoči na glavni sadržaj

Arhiv za higijenu rada i toksikologiju, Vol. 27 No. 4, 1976.

Pregledni rad

Biologically active adamantane derivatives

Z. Majerski ; Institut »Ruder Bošković« u Zagrebu
D. Škare ; Institut »Ruder Bošković« u Zagrebu
J. Janjatović ; Institut »Ruder Bošković« u Zagrebu
Z. Hameršak ; Institut »Ruder Bošković« u Zagrebu
B. Vinković ; Institut »Ruder Bošković« u Zagrebu

Puni tekst: hrvatski pdf 7.404 Kb

str. 335-344

preuzimanja: 382

citiraj

Sažetak

Adamantane derivatives cover a very broad spectrum of biological activities. In this review characteristic examples are described: virustatics and antiparkinsonics, antibiotics, cytostatics, hypoglycemics, sedatives and antidepressants, antiarrythmics and antihypertonics, immunosuppressive agents and spasmolytics. A higher biological activity of adamantane derivatives than that of some known drugs is a consequence of their higher lipophilicity more rapid transport through cell membranes and higher resistance to metabolitic degradation.

Ključne riječi

Hrčak ID:

165737

URI

https://hrcak.srce.hr/165737

Datum izdavanja:

15.3.1977.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.187 *