Croatica Chemica Acta, Vol. 49 No. 2, 1977.
Conference paper
The Mode of Binding of Carbon Monoxide to Iron in Cytochrome P450 and Cytochrome P420. An Infrared Study
H. Rein
; Department of Methods and Theory and Department of Biocatalysis, Central Institute of Molecular Biology, Acader;iy of Sciences of the GDR, 1115 Berlin, GDR
S. Bohm
; Department of Methods and Theory and Department of Biocatalysis, Central Institute of Molecular Biology, Acader;iy of Sciences of the GDR, 1115 Berlin, GDR
G.-R. Janig
; Department of Methods and Theory and Department of Biocatalysis, Central Institute of Molecular Biology, Acader;iy of Sciences of the GDR, 1115 Berlin, GDR
K. Ruckpaul
; Department of Methods and Theory and Department of Biocatalysis, Central Institute of Molecular Biology, Acader;iy of Sciences of the GDR, 1115 Berlin, GDR
Abstract
The infrared stretching vibrations (vc0 ) of the CO-complexes
of cytochrome P450 and cytochrome P420 have been determined
from the infrared difference spectra. The CO-complexes exhibit
ir-bands at 1949 cm-1 and 1966 cm-1 with half widths of -17 cm·1
and - 20 cm·1 respectively. These results are con;ipared with the
CO-stretching frequencies of other hemoproteins and discussed with
respect to specific interactions of the CO-ligand with the protein
moiety and to the ligand trans to CO in the cytochrome.
Keywords
Hrčak ID:
196372
URI
Publication date:
30.3.1977.
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