Croatica Chemica Acta, Vol. 92 No. 1, 2019.
Izvorni znanstveni članak
https://doi.org/10.5562/cca3475
Helichrysum italicum (Roth) G. Don subsp. italicum from Herzegovina: Volatile Composition, Variations during Seasons, Total Polyphenols, Acetylcho-linesterase Inhibition and Antioxidant Activity
Stanislava Talić
orcid.org/0000-0001-7633-4312
; Department of Chemistry, Faculty of Science and Education, University of Mostar, Matice hrvatske bb, 88000 Mostar, Bosnia and Herzegovina
Ilijana Odak
orcid.org/0000-0002-6883-8470
; Department of Chemistry, Faculty of Science and Education, University of Mostar, Matice hrvatske bb, 88000 Mostar, Bosnia and Herzegovina
Anita Martinović Bevanda
; Department of Chemistry, Faculty of Science and Education, University of Mostar, Matice hrvatske bb, 88000 Mostar, Bosnia and Herzegovina
Nikolina Crnjac
; Department of Chemistry, Faculty of Science and Education, University of Mostar, Matice hrvatske bb, 88000 Mostar, Bosnia and Herzegovina
Mate Paštar
; Department of Chemistry, Faculty of Science and Education, University of Mostar, Matice hrvatske bb, 88000 Mostar, Bosnia and Herzegovina
Sažetak
The chemical composition of essential oils isolated from immortelle (Helicrysum italicum subsp. italicum) collected in Herzegovina during five different periods, was investigated by GC/MS analysis. The main compounds were a-pinene (15.7 %) and γ-curcumene (12.8 %), followed by 4,6,9-trimethyldec-8-en-3,5-dione (8.7 %), neryl acetate (6.9 %), limonene (6.4 %) and β-selinene (5.3 %). In total, 69 components were identified whose share changed over the vegetative cycle. Antioxidant activity of methanolic extracts of immortelle were determined according to DPPH (IC50 = 23–34 μg/mL) and FRAP (29 μg/mL is equivalent to 1.1‒2.2 mM Fe2+) methods. Acetylcholinesterase inhibitory potential, investigated by modified Ellman’s assay and determined as IC50 values, were 340–440 μg/mL for methanol extracts and 135 μg/mL for essential oil. Metanolic extracts showed strong antioxidant activity and potential to inhibit AChE. Essential oil possesses complex chemical composition, inhibition activity of AChE and weak antioxidant capacity.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Ključne riječi
Helichrysum italicum subsp. italicum; Asteraceae; essential oil composition; α-pinene; γ-curcumene; antioxidant activity
Hrčak ID:
218125
URI
Datum izdavanja:
28.1.2019.
Posjeta: 3.223 *