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An unknown horse disease appeared in Mraclin 80 years ago - what caused “Mraclin horse disease“?

Željko Cvetnić ; Veterinarski zavod Križevci, Hrvatski veterinarski institut, Zagreb, Hrvatska
Tomislav Sukalić ; Veterinarski zavod Križevci, Hrvatski veterinarski institut, Zagreb, Hrvatska
Vladimir Savić ; Centar za peradarstvo, Hrvatski veterinarski institut, Zagreb, Hrvatska
Željko Grabarević ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska


Puni tekst: hrvatski pdf 670 Kb

str. 201-210

preuzimanja: 786

citiraj


Sažetak

An acute neurological disease of horses appeared sporadically in September and October of 1938 in the villages of Rakarje, Buševec and Kurilovec in the Turopolje area, and as a limited epizootic event in Mraclin. The disease was named “Mraclin Horse Disease” (MHD). Of the 442 horses in the village, 200 came down with clinical signs and were treated, and 25 perished. All the affected horses had virtually identical acute neurological symptoms. The cause of the disease has not yet been proven, but the great similarity between the clinical signs of MHD with encephalomyelitis caused by the West Nile virus (WNV), suggested that WNV may have caused MHD in 1938. However, analysis of the pathological and pathohistological findings of horses that perished from MHD indicated massive necrosis of the liver caused by unknown toxin as the main cause of death. Neurological symptoms are a consequence of hepatic encephalopathy, and bleeding and icterus are obvious consequences of liver dysfunction. It can therefore be concluded that one of the possible causes of death was intoxication. This conclusion is based on the pathological findings of 1938, found in the archives of the Department of Pathology, Faculty of Veterinary Medicine, University of Zagreb. Another question that arises is what caused the poisoning of these horses? Differential diagnosis is difficult, but it is not impossible to exclude viral pathogens such as WNV, which would certainly help to detect the causative agent of MHD in 1938.

Ključne riječi

Mraclin; horse disease; Western Nile virus; intoxication

Hrčak ID:

223827

URI

https://hrcak.srce.hr/223827

Datum izdavanja:

11.6.2019.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.815 *