Izvorni znanstveni članak
Genetic sub-structuring of Croatian island populations in the Southeastern European context: a meta-analysis
Natalija Novokmet
; Institute for Anthropological Research, Zagreb, Croatia
Ana Galov
; Department of Animal Physiology, Faculty of Science, Zagreb, Croatia
Vedrana Škaro
; DNA Laboratory, Genos Ltd., Zagreb, Croatia
Petar Projić
; DNA Laboratory, Genos Ltd., Zagreb, Croatia
Jelena Šarac
; St. Catherine Hospital, Zagreb, Croatia
Dubravka Havaš Auguštin
; Institute for Anthropological Research, Zagreb, Croatia
Pavao Rudan
; Scientific Council for Anthropological Research, Croatian Academy of Sciences and Arts, Zagreb, Croatia
Dragan Primorac
; St. Catherine Hospital, Zagreb, Croatia
Damir Marjanović
; Department of Genetics and Bioengineering, International Burch University, Sarajevo, Bosnia and Herzegovina
Sažetak
Aim To use the method of meta-analysis to assess the influence of island population isolation on the sub-structuring of the Croatian population, as well as the influence of
regional population groups on the sub-structuring of the
Southeastern European population with regard to basic
population genetic statistical parameters calculated by using STR locus analysis.
Methods Bio-statistical analyses were performed for 2877
unrelated participants of both sexes from Southeastern Europe. Nine autosomal STR loci (D3S1358, vWA, FGA, TH01,
TPOX, CSF1PO, D5S818, D13S317, and D7S82) were analyzed by using standard F-statistics and population structure analysis (Structure software).
Results Genetic differentiation of Croatian subpopulations
assessed with the FST method was higher at the level of
the Croatian population (0.005) than at the level of Southeastern Europe (0.002). The island of Vis showed the most
pronounced separation in the Croatian population, and Albanians from Kosovo in the population of Southeast Europe, followed by Croatia, Bosnia and Herzegovina, and
Hungary.
Conclusion The higher structure of Croatian subpopulations in relation to Southeastern Europe suggest a certain
degree of genetic isolation, most likely due to the influence of endogamy within rural island populations.
Ključne riječi
Hrčak ID:
290154
URI
Datum izdavanja:
23.6.2022.
Posjeta: 706 *