Recenzija, Prikaz slučaja
Target Intraocular Pressure in the Management of Glaucoma
Smiljka Popović-Suić
Jakov Šikić
Nenad Vukojević
Branimir Cerovski
Mirjana Nasić
Rajko Pokupec
Sažetak
Achievement of target intraocular pressure is the goal of every efficient antiglaucoma therapy. Target intraocular
pressure is the level of intraocular pressure which is associated with minimal likelihood of visual field or optic nerve lesion,
or an existing lesion progression due to elevated intraocular pressure. Results of large clinical studies which have
offered some new concepts on target intraocular pressure in the management of glaucoma are reviewed. An association
between the curve of intraocular pressure decrease and glaucoma progression was demonstrated in these studies. Generally,
a lower value of target intraocular pressure implies better protection from the loss of vision and visual field impairment
in glaucoma patients. In advanced glaucoma, the greatest possible reduction from the initial intraocular
pressure should be attempted. A 20% reduction from the initial intraocular pressure or decrease to <18 mmHg in advanced
glaucoma has been recognized as a favorable strategy to reach target intraocular pressure. In normal tension
glaucoma, a lower value of target intraocular pressure is associated with a slower disease progression. In patients with
initial glaucoma, 25% reduction from the initial intraocular pressure will slow down the disease progression by 45%.
The value of target intraocular pressure depends on the pretreatment level of intraocular pressure, optic nerve condition,
glaucoma disease state, rate of glaucoma progression, patient's age, and other risk factors for the development of
glaucoma.
Ključne riječi
target intraocular pressure; glaucoma; management
Hrčak ID:
27908
URI
Datum izdavanja:
20.6.2005.
Posjeta: 2.683 *