Acta clinica Croatica, Vol. 63. No. 1, 2024.
Izvorni znanstveni članak
https://doi.org/10.20471/acc.2024.63.01.3
Early onset of multiple sclerosis - clinical features
Vesna Suknjaja
; University Clinical Center of Vojvodina, Department of Neuroinfl ammation and Demyelinization, Novi Sad, Serbia; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia
*
Lorand Sakalaš
; University Clinical Center of Vojvodina, Department of Neuroinfl ammation and Demyelinization, Novi Sad, Serbia; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia
Miroslav Ilin
; University Clinical Center of Vojvodina, Department of Neuromuscular and Spinal Diseases, Novi Sad, Serbia
* Dopisni autor.
Sažetak
The onset of multiple sclerosis (MS) in childhood is a diagnostic challenge. The aim
of our study was to analyze the parameters of MS with an early onset in relation to the symptoms and
course of the disease in adult patients. Th is study included patients treated with signs and symptoms
of initial central nervous system demyelinating disease, which were divided into a group of 52 patients
who developed the disease before the age of 18 (children) and another group aged 20-55 years
(adults). Children rarely had polysymptomatic onset (p=0.020). The most common initial symptoms
in children were optic neuritis (35.3%) and ataxia (35.3%). In the group of adult patients, sensory
disturbances (41.6%) were the most common initial symptoms, followed by pyramidal symptoms
(37.6%). Monitoring the time of second relapse revealed it to have occurred in 40 (78.4%) pediatric
patients and 79 (78.2%) adult patients after a median of 12 months and 9 months, respectively.
In conclusion, the initial manifestations of MS in children do not differ much from MS in adults
according to the disease characteristics.
Ključne riječi
Multiple sclerosis, pediatric; Multiple sclerosis, adulthood; Clinical presentation of disease
Hrčak ID:
322009
URI
Datum izdavanja:
1.4.2024.
Posjeta: 0 *