Socijalna psihijatrija, Vol. 54 No. 2, 2026.
Sažetak sa skupa
https://doi.org/10.24869/spsih.2026.212
From Diagnosis to Trajectory: A Transsyndromal and Developmental Model of Psychopathology in Youth
Tomislav Franić
; Klinički bolnički centar Split, Split, Hrvatska; Medicinski fakultet, Sveučilište u Splitu, Split, Hrvatska
*
Mia Plenković
; Medicinski fakultet, Sveučilište u Splitu, Split, Hrvatska
Nada Gruja
; Medicinski fakultet, Sveučilište u Splitu, Split, Hrvatska
Tonći Mastelić
; Klinički bolnički centar Split, Split, Hrvatska
Frane Franić
; Medicinski fakultet, Sveučilište u Zagrebu, Zagreb, Hrvatska
Jakša Vukojević
; Medicinski fakultet, Sveučilište u Zagrebu, Zagreb, Hrvatska; Klinika za psihijatriju Vrapče, Zagreb, Hrvatska
Youth- GEMs
; Sveučilište u Maastrichtu, Maastricht, Nizozemska
* Dopisni autor.
Sažetak
Research objectives: The psychopathology of adolescence
and early adulthood is characterized by
symptom overlap, fluctuations in clinical presentation,
and transitions between different mental
disorders across development. This dynamic poses
a challenge for traditional diagnostic systems.
Contemporary developmental models emphasize
a continuum of mental phenotypes, shared biological
and environmental mechanisms, and the importance
of understanding individual developmental
trajectories. The aim of this paper is to present
a transsyndromal approach to psychopathology
in young people and its potential for the development of prognostic models. Materials and methods:
The conceptual framework of the Youth-GEMs
project is presented, which investigates developmental
trajectories of mental health by integrating
clinical, genetic, epigenetic, and environmental
data. Emphasis is placed on developmental transitions
between psychopathological phenomena,
transsyndromal patterns of help-seeking, and the
concept of clinical staging. Statistical analysis: Longitudinal
models, multivariate analyses, and artificial
intelligence algorithms were applied to identify
developmental patterns of psychopathology and to
develop individualized prognostic models. Results:
The study is expected to identify developmental
patterns that transcend traditional diagnostic categories
and to provide a better understanding of
the links between developmental neurobiological
processes and later psychopathological outcomes.
A particular strength of this approach is early risk
detection, before the emergence of clearly defined
disorders. Conclusion: The transsyndromal approach
represents a shift away from symptom-defined
diagnoses toward a developmental and etiopathogenetic
understanding of psychopathology.
Such a model enables the development of more
precise, personalized, and prognostically oriented
psychiatry and helps bridge the traditional divide
between child and adult psychiatry.
Ključne riječi
transsyndromal psychopathology; developmental trajectories; clinical staging; precision psychiatry; youth mental health
Hrčak ID:
352337
URI
Datum izdavanja:
15.6.2026.
Posjeta: 0 *