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Differential Diagnostic Performance of Rose Bengal Score Test in Sjøgren’s Syndrome Patients

Igor Knezović
Ivan Alajbeg
Dalibor Karlović
Josip Pavan
Nada Vrkić
Ana Bišćan

Puni tekst: engleski, pdf (139 KB) str. 1105-1113 preuzimanja: 268* citiraj
APA 6th Edition
Knezović, I., Alajbeg, I., Karlović, D., Pavan, J., Vrkić, N. i Bišćan, A. (2011). Differential Diagnostic Performance of Rose Bengal Score Test in Sjøgren’s Syndrome Patients. Collegium antropologicum, 35 (4), 1105-1113. Preuzeto s https://hrcak.srce.hr/75614
MLA 8th Edition
Knezović, Igor, et al. "Differential Diagnostic Performance of Rose Bengal Score Test in Sjøgren’s Syndrome Patients." Collegium antropologicum, vol. 35, br. 4, 2011, str. 1105-1113. https://hrcak.srce.hr/75614. Citirano 20.11.2019.
Chicago 17th Edition
Knezović, Igor, Ivan Alajbeg, Dalibor Karlović, Josip Pavan, Nada Vrkić i Ana Bišćan. "Differential Diagnostic Performance of Rose Bengal Score Test in Sjøgren’s Syndrome Patients." Collegium antropologicum 35, br. 4 (2011): 1105-1113. https://hrcak.srce.hr/75614
Harvard
Knezović, I., et al. (2011). 'Differential Diagnostic Performance of Rose Bengal Score Test in Sjøgren’s Syndrome Patients', Collegium antropologicum, 35(4), str. 1105-1113. Preuzeto s: https://hrcak.srce.hr/75614 (Datum pristupa: 20.11.2019.)
Vancouver
Knezović I, Alajbeg I, Karlović D, Pavan J, Vrkić N, Bišćan A. Differential Diagnostic Performance of Rose Bengal Score Test in Sjøgren’s Syndrome Patients. Collegium antropologicum [Internet]. 2011 [pristupljeno 20.11.2019.];35(4):1105-1113. Dostupno na: https://hrcak.srce.hr/75614
IEEE
I. Knezović, I. Alajbeg, D. Karlović, J. Pavan, N. Vrkić i A. Bišćan, "Differential Diagnostic Performance of Rose Bengal Score Test in Sjøgren’s Syndrome Patients", Collegium antropologicum, vol.35, br. 4, str. 1105-1113, 2011. [Online]. Dostupno na: https://hrcak.srce.hr/75614. [Citirano: 20.11.2019.]

Sažetak
Aim of the study was to evaluate the diagnostic performance of the Rose Bengal score test for Sjøgren’s syndrome
(SS), and to explore differences between other tests and examinations. All participants were examined, including (but not
limited to) unstimulated (UWS) and stimulated (SWS) whole saliva, labial gland biopsy (LGB or focus score), ophthalmologic
questionnaire (ocular surface disease index OSDI) and objective tests: Schirmer test 1 (Sch.1), Schirmer test
2 (Sch.2), Tear Break-up Time (TBUT) test and Rose Bengal score (RBS). Data were analyzed using Mann Whitney
U-test, Receiver Operating Characteristic analysis, with specificity and sensitivity calculations and Spearman’s correlation
test. ROC curves showed a poor diagnostic performance of TBUT and OSDI. Sch.1, Sch.2 and LGB all exhibited
a high diagnostic performance. RBS exhibited the best performance (sensitivity 100,00; specificity 100,00; AUC
1,000). Study reveals the scarce reliability of TBUT, OSDI and Sch.1, and emphasizes RBS as the test of choice in the
SS diagnosis.

Ključne riječi
Rose Bengal; Sjøgren’s syndrome; Keratokonjunctivitis Sicca; Xerostomia; salivary gland diseases; Tear Break-Up Time test; ophthalmologic questionnaire; labial gland biopsy

Hrčak ID: 75614

URI
https://hrcak.srce.hr/75614

Posjeta: 443 *