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Retinoids in Mammals: A Crystallographic Perspective

Giuseppe Zanotti ; Department of Organic Chemistry, University of Padova and Biopolymer Research Center, C.N.R., Via Marzolo 1, 35131 Padova, Italy
Rodolfo Berni ; Department of Biochemistry and Molecular Biology, University of Parma, Parco Area delle Scienze 231 A, 43100 Parma, Italy

Puni tekst: engleski, pdf (117 KB) str. 835-845 preuzimanja: 181* citiraj
APA 6th Edition
Zanotti, G. i Berni, R. (2002). Retinoids in Mammals: A Crystallographic Perspective. Croatica Chemica Acta, 75 (3), 835-845. Preuzeto s https://hrcak.srce.hr/129325
MLA 8th Edition
Zanotti, Giuseppe i Rodolfo Berni. "Retinoids in Mammals: A Crystallographic Perspective." Croatica Chemica Acta, vol. 75, br. 3, 2002, str. 835-845. https://hrcak.srce.hr/129325. Citirano 28.02.2021.
Chicago 17th Edition
Zanotti, Giuseppe i Rodolfo Berni. "Retinoids in Mammals: A Crystallographic Perspective." Croatica Chemica Acta 75, br. 3 (2002): 835-845. https://hrcak.srce.hr/129325
Harvard
Zanotti, G., i Berni, R. (2002). 'Retinoids in Mammals: A Crystallographic Perspective', Croatica Chemica Acta, 75(3), str. 835-845. Preuzeto s: https://hrcak.srce.hr/129325 (Datum pristupa: 28.02.2021.)
Vancouver
Zanotti G, Berni R. Retinoids in Mammals: A Crystallographic Perspective. Croatica Chemica Acta [Internet]. 2002 [pristupljeno 28.02.2021.];75(3):835-845. Dostupno na: https://hrcak.srce.hr/129325
IEEE
G. Zanotti i R. Berni, "Retinoids in Mammals: A Crystallographic Perspective", Croatica Chemica Acta, vol.75, br. 3, str. 835-845, 2002. [Online]. Dostupno na: https://hrcak.srce.hr/129325. [Citirano: 28.02.2021.]

Sažetak
Retinoids are involved in several essential processes in mammals, including vision, morphogenesis, spermatogenesis and maintenance of epithelial tissue. Since they are labile compounds, nearly insoluble in water, they are present in body fluids and within the cell bound to specific retinoid-binding proteins. In plasma, a single protein, called retinol-binding protein, delivers the alcoholic form of vitamin A from its store sites to target cells. In the cytoplasm, four different cellular retinol-binding proteins and two retinoic acid-binding proteins have been discovered and structurally characterized to date. Finally, two classes of nuclear receptors for retinoic acid isomers have been characterized. The structure/function relationship for several retinoid-binding proteins is discussed here.

Ključne riječi
vitamin A; retinol; retinoids; retinoic acid; retinol-binding proteins; retinoid receptors; crystal structure

Hrčak ID: 129325

URI
https://hrcak.srce.hr/129325

Posjeta: 311 *