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Some important aspects of implementing tandem mass spectrometry in a routine clinical laboratory environment

Christoph Seger
Andrea Griesmacher

Puni tekst: engleski, pdf (691 KB) str. 29-51 preuzimanja: 344* citiraj
APA 6th Edition
Seger, C. i Griesmacher, A. (2007). Some important aspects of implementing tandem mass spectrometry in a routine clinical laboratory environment. Biochemia Medica, 17 (1), 29-51. Preuzeto s https://hrcak.srce.hr/12858
MLA 8th Edition
Seger, Christoph i Andrea Griesmacher. "Some important aspects of implementing tandem mass spectrometry in a routine clinical laboratory environment." Biochemia Medica, vol. 17, br. 1, 2007, str. 29-51. https://hrcak.srce.hr/12858. Citirano 17.01.2021.
Chicago 17th Edition
Seger, Christoph i Andrea Griesmacher. "Some important aspects of implementing tandem mass spectrometry in a routine clinical laboratory environment." Biochemia Medica 17, br. 1 (2007): 29-51. https://hrcak.srce.hr/12858
Harvard
Seger, C., i Griesmacher, A. (2007). 'Some important aspects of implementing tandem mass spectrometry in a routine clinical laboratory environment', Biochemia Medica, 17(1), str. 29-51. Preuzeto s: https://hrcak.srce.hr/12858 (Datum pristupa: 17.01.2021.)
Vancouver
Seger C, Griesmacher A. Some important aspects of implementing tandem mass spectrometry in a routine clinical laboratory environment. Biochemia Medica [Internet]. 2007 [pristupljeno 17.01.2021.];17(1):29-51. Dostupno na: https://hrcak.srce.hr/12858
IEEE
C. Seger i A. Griesmacher, "Some important aspects of implementing tandem mass spectrometry in a routine clinical laboratory environment", Biochemia Medica, vol.17, br. 1, str. 29-51, 2007. [Online]. Dostupno na: https://hrcak.srce.hr/12858. [Citirano: 17.01.2021.]
Puni tekst: hrvatski, pdf (691 KB) str. 29-51 preuzimanja: 667* citiraj
APA 6th Edition
Seger, C. i Griesmacher, A. (2007). Važni aspekti uspostave dvojne spektrometrije masa u uvjetima rutinskoga kliničkog laboratorija. Biochemia Medica, 17 (1), 29-51. Preuzeto s https://hrcak.srce.hr/12858
MLA 8th Edition
Seger, Christoph i Andrea Griesmacher. "Važni aspekti uspostave dvojne spektrometrije masa u uvjetima rutinskoga kliničkog laboratorija." Biochemia Medica, vol. 17, br. 1, 2007, str. 29-51. https://hrcak.srce.hr/12858. Citirano 17.01.2021.
Chicago 17th Edition
Seger, Christoph i Andrea Griesmacher. "Važni aspekti uspostave dvojne spektrometrije masa u uvjetima rutinskoga kliničkog laboratorija." Biochemia Medica 17, br. 1 (2007): 29-51. https://hrcak.srce.hr/12858
Harvard
Seger, C., i Griesmacher, A. (2007). 'Važni aspekti uspostave dvojne spektrometrije masa u uvjetima rutinskoga kliničkog laboratorija', Biochemia Medica, 17(1), str. 29-51. Preuzeto s: https://hrcak.srce.hr/12858 (Datum pristupa: 17.01.2021.)
Vancouver
Seger C, Griesmacher A. Važni aspekti uspostave dvojne spektrometrije masa u uvjetima rutinskoga kliničkog laboratorija. Biochemia Medica [Internet]. 2007 [pristupljeno 17.01.2021.];17(1):29-51. Dostupno na: https://hrcak.srce.hr/12858
IEEE
C. Seger i A. Griesmacher, "Važni aspekti uspostave dvojne spektrometrije masa u uvjetima rutinskoga kliničkog laboratorija", Biochemia Medica, vol.17, br. 1, str. 29-51, 2007. [Online]. Dostupno na: https://hrcak.srce.hr/12858. [Citirano: 17.01.2021.]

Sažetak
During past years, the combination of high performance liquid chromatography (HPLC) and tandem mass spectrometry (MS/MS), also known as HPLC-MS/MS, matured to reliable analytical instrumentation. Its application in therapeutic drug monitoring (TDM) has been shown to be superior to normally applied immunoassays. Especially in the context of immunosuppressant medication level surveillance, this technique has become an indispensable tool in many clinical laboratories and is considered the gold standard. However, setting up a HPLC-MS/MS platform is demanding in terms of assay validation and the robustness of testing. This review is to provide a rough guideline aiding the implementation process of such a platform into a routine clinical environment.

Ključne riječi
tandem mass spectrometry; targeted analysis; therapeutic drug monitoring; routine analysis; high performance liquid chromatography; HPLC-MS/MS

Hrčak ID: 12858

URI
https://hrcak.srce.hr/12858

[hrvatski]

Posjeta: 1.602 *