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Dihydropyridine Isomerism in the Chemical Delivery System Series

Emil Pop ; Pharmos Corporation, 2 Innovation Drive, Alachua, FL. 32615
Marcus E. Brewster ; Pharmos Corporation, 2 Innovation Drive, Alachua, FL. 32615
Ming-Ju Huang ; Center for Drug Discovery, College of Pharmacy, University of Florida, Gainesville, FL. 32610
Nicholas Bodor ; Pharmos Corporation, 2 Innovation Drive, Alachua, FL. 32615

Puni tekst: engleski, pdf (15 MB) str. 531-537 preuzimanja: 211* citiraj
APA 6th Edition
Pop, E., Brewster, M.E., Huang, M. i Bodor, N. (1993). Dihydropyridine Isomerism in the Chemical Delivery System Series. Croatica Chemica Acta, 66 (3-4), 531-537. Preuzeto s https://hrcak.srce.hr/137054
MLA 8th Edition
Pop, Emil, et al. "Dihydropyridine Isomerism in the Chemical Delivery System Series." Croatica Chemica Acta, vol. 66, br. 3-4, 1993, str. 531-537. https://hrcak.srce.hr/137054. Citirano 24.02.2021.
Chicago 17th Edition
Pop, Emil, Marcus E. Brewster, Ming-Ju Huang i Nicholas Bodor. "Dihydropyridine Isomerism in the Chemical Delivery System Series." Croatica Chemica Acta 66, br. 3-4 (1993): 531-537. https://hrcak.srce.hr/137054
Harvard
Pop, E., et al. (1993). 'Dihydropyridine Isomerism in the Chemical Delivery System Series', Croatica Chemica Acta, 66(3-4), str. 531-537. Preuzeto s: https://hrcak.srce.hr/137054 (Datum pristupa: 24.02.2021.)
Vancouver
Pop E, Brewster ME, Huang M, Bodor N. Dihydropyridine Isomerism in the Chemical Delivery System Series. Croatica Chemica Acta [Internet]. 1993 [pristupljeno 24.02.2021.];66(3-4):531-537. Dostupno na: https://hrcak.srce.hr/137054
IEEE
E. Pop, M.E. Brewster, M. Huang i N. Bodor, "Dihydropyridine Isomerism in the Chemical Delivery System Series", Croatica Chemica Acta, vol.66, br. 3-4, str. 531-537, 1993. [Online]. Dostupno na: https://hrcak.srce.hr/137054. [Citirano: 24.02.2021.]

Sažetak
A theoretical study was performed for three structured isomers of the dihydropyridine-targetor btised chemical delivery systems of estradiol euid azidothymine. The relative thermodynamic stabilities reflected by the calculated heats of formation (AHf) indicated, in good agreement with avedlable experimental evidence, preferential formation of the 1,4-dihydropyridine isomers as a result of thermodynamic product control. The increased relative stability of the 1,4-isomers, as compared to the 1,2-and 1,6-dihydropyridine, is explained by favorable electronic interactions (hyperconjugation, homoarom- aticily) existent in these derivatives.

Hrčak ID: 137054

URI
https://hrcak.srce.hr/137054

Posjeta: 340 *