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Review article

Glucocorticoid induced osteoporosis

Branimir Anić ; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine of the School of Medicine, University of Zagreb, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Miroslav Mayer ; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine of the School of Medicine, University of Zagreb, Clinical Hospital Centre Zagreb, Zagreb, Croatia

Fulltext: croatian, pdf (490 KB) pages 105-112 downloads: 294* cite
APA 6th Edition
Anić, B. & Mayer, M. (2014). Glukokortikoidima izazvana osteoporoza. Reumatizam, 61 (2), 105-112. Retrieved from https://hrcak.srce.hr/137907
MLA 8th Edition
Anić, Branimir and Miroslav Mayer. "Glukokortikoidima izazvana osteoporoza." Reumatizam, vol. 61, no. 2, 2014, pp. 105-112. https://hrcak.srce.hr/137907. Accessed 15 Jan. 2021.
Chicago 17th Edition
Anić, Branimir and Miroslav Mayer. "Glukokortikoidima izazvana osteoporoza." Reumatizam 61, no. 2 (2014): 105-112. https://hrcak.srce.hr/137907
Harvard
Anić, B., and Mayer, M. (2014). 'Glukokortikoidima izazvana osteoporoza', Reumatizam, 61(2), pp. 105-112. Available at: https://hrcak.srce.hr/137907 (Accessed 15 January 2021)
Vancouver
Anić B, Mayer M. Glukokortikoidima izazvana osteoporoza. Reumatizam [Internet]. 2014 [cited 2021 January 15];61(2):105-112. Available from: https://hrcak.srce.hr/137907
IEEE
B. Anić and M. Mayer, "Glukokortikoidima izazvana osteoporoza", Reumatizam, vol.61, no. 2, pp. 105-112, 2014. [Online]. Available: https://hrcak.srce.hr/137907. [Accessed: 15 January 2021]

Abstracts
Secondary osteoporosis most often develops due to glucocorticoid therapy. Glucocorticoids affect all stages of the bone remodeling cycle, its formation and resorption. Osteoblasts are primarily affected, decreasing their activity and enhancing apoptosis. Patients treated with glucocorticoids have lower bone mineral density and increased fracture risk. Glucocorticoid-induced osteoporosis can be prevented by administering the minimal effective dose of glucocorticoids, calcium and vitamin D supplementation or, if possible, by hormone replacement therapy. Moreover, appropriate physical activity should be encouraged. Patients who are at higher risk for low-energy fractures (for example post-menopausal women) have to be actively treated, usually with antiresorptive drugs among which bisphosphonates are currently the first line therapy.

Keywords
osteoporosis; glucocorticoids; diagnostics; prevention; treatment

Hrčak ID: 137907

URI
https://hrcak.srce.hr/137907

[croatian]

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