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Measurement of the distribution of m-xylene in rat tissues by head space gas chromatography

Prem Kumarathasan ; Environmental Health Centre, Room 332, PL 0803C, Tunne/s Pasture, Ottawa (Ont) K1A 0L2, Canada
Rein Otson
Ih Chu

Puni tekst: engleski, pdf (5 MB) str. 373-381 preuzimanja: 183* citiraj
APA 6th Edition
Kumarathasan, P., Otson, R. i Chu, I. (1997). Measurement of the distribution of m-xylene in rat tissues by head space gas chromatography. Arhiv za higijenu rada i toksikologiju, 48 (4), 373-381. Preuzeto s https://hrcak.srce.hr/144267
MLA 8th Edition
Kumarathasan, Prem, et al. "Measurement of the distribution of m-xylene in rat tissues by head space gas chromatography." Arhiv za higijenu rada i toksikologiju, vol. 48, br. 4, 1997, str. 373-381. https://hrcak.srce.hr/144267. Citirano 27.02.2021.
Chicago 17th Edition
Kumarathasan, Prem, Rein Otson i Ih Chu. "Measurement of the distribution of m-xylene in rat tissues by head space gas chromatography." Arhiv za higijenu rada i toksikologiju 48, br. 4 (1997): 373-381. https://hrcak.srce.hr/144267
Harvard
Kumarathasan, P., Otson, R., i Chu, I. (1997). 'Measurement of the distribution of m-xylene in rat tissues by head space gas chromatography', Arhiv za higijenu rada i toksikologiju, 48(4), str. 373-381. Preuzeto s: https://hrcak.srce.hr/144267 (Datum pristupa: 27.02.2021.)
Vancouver
Kumarathasan P, Otson R, Chu I. Measurement of the distribution of m-xylene in rat tissues by head space gas chromatography. Arh Hig Rada Toksikol. [Internet]. 1997 [pristupljeno 27.02.2021.];48(4):373-381. Dostupno na: https://hrcak.srce.hr/144267
IEEE
P. Kumarathasan, R. Otson i I. Chu, "Measurement of the distribution of m-xylene in rat tissues by head space gas chromatography", Arhiv za higijenu rada i toksikologiju, vol.48, br. 4, str. 373-381, 1997. [Online]. Dostupno na: https://hrcak.srce.hr/144267. [Citirano: 27.02.2021.]

Sažetak
An automated head space-gas chromatography (HS-GC) method was developed and evaluated for reliability in measurement of m-xylene in rat tissues. For tissue samples spiked with m-xylene (n=2), the analytical precision was better than 12% relative standard deviation (RSD) over the concentration range of 0.1 to cca 100 µg/g for liver and kidney, 0.1 to 170 µg/g for brain, 1.2 to 250 µg/g for fat, and 0.006 to 50 µg/mL for blood. For rats sacrificed immediately after an acute exposure to 1100 ppm of m-xylene, the relative tissue m-xylene concentrations were in the ascending order as follows: brain ≤ blood ≤kidney ≤ liver « fat. A precision of < 13% RSD was generally obtained for duplicale tissue samples from exposed animals, with m-xylene concentrations of about 10 µg/g of tissue.

Ključne riječi
automated HS-GC method; blood; distribution; inhalation exposure; m-xylene; tissue

Hrčak ID: 144267

URI
https://hrcak.srce.hr/144267

[hrvatski]

Posjeta: 353 *