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WHEN DO PSYCHIATRIC SIDE EFFECTS EMERGE DURING ANTIVIRAL TREATMENT OF HEPATITIS C?

Gábor Gazdag   ORCID icon orcid.org/0000-0002-6914-8041 ; Center for Psychiatry and Addiction Medicine, Szent István and Szent László Hospital, Budapest, Hungary; Department of Psychiatry and Psychotherapy, Semmelweis University, Faculty of Medicine, Budapest, Hungary
Gergely Horváth ; Hungarian Drug Focal Point, National Center for Epidemiology, Budapest, Hungary
Olga Szabó ; Hepatology Outpatient Clinic, Szent István and Szent László Hospitals, Budapest, Hungary
Rozália Takács ; 1st Department of Psychiatry, Nyirö Gyula Hospital, Budapest, Hungary
Gabor S. Ungvari ; University of Notre Dame Australia/Marian Centre, Perth, Australia; School of Psychiatry & Clinical Neurosciences, University of Western Australia, Perth, Australia

Puni tekst: engleski, pdf (160 KB) str. 0-400 preuzimanja: 100* citiraj
APA 6th Edition
Gazdag, G., Horváth, G., Szabó, O., Takács, R. i S. Ungvari, G. (2013). WHEN DO PSYCHIATRIC SIDE EFFECTS EMERGE DURING ANTIVIRAL TREATMENT OF HEPATITIS C?. Psychiatria Danubina, 25 (4), 0-400. Preuzeto s https://hrcak.srce.hr/162116
MLA 8th Edition
Gazdag, Gábor, et al. "WHEN DO PSYCHIATRIC SIDE EFFECTS EMERGE DURING ANTIVIRAL TREATMENT OF HEPATITIS C?." Psychiatria Danubina, vol. 25, br. 4, 2013, str. 0-400. https://hrcak.srce.hr/162116. Citirano 24.10.2020.
Chicago 17th Edition
Gazdag, Gábor, Gergely Horváth, Olga Szabó, Rozália Takács i Gabor S. Ungvari. "WHEN DO PSYCHIATRIC SIDE EFFECTS EMERGE DURING ANTIVIRAL TREATMENT OF HEPATITIS C?." Psychiatria Danubina 25, br. 4 (2013): 0-400. https://hrcak.srce.hr/162116
Harvard
Gazdag, G., et al. (2013). 'WHEN DO PSYCHIATRIC SIDE EFFECTS EMERGE DURING ANTIVIRAL TREATMENT OF HEPATITIS C?', Psychiatria Danubina, 25(4), str. 0-400. Preuzeto s: https://hrcak.srce.hr/162116 (Datum pristupa: 24.10.2020.)
Vancouver
Gazdag G, Horváth G, Szabó O, Takács R, S. Ungvari G. WHEN DO PSYCHIATRIC SIDE EFFECTS EMERGE DURING ANTIVIRAL TREATMENT OF HEPATITIS C?. Psychiatria Danubina [Internet]. 2013 [pristupljeno 24.10.2020.];25(4):0-400. Dostupno na: https://hrcak.srce.hr/162116
IEEE
G. Gazdag, G. Horváth, O. Szabó, R. Takács i G. S. Ungvari, "WHEN DO PSYCHIATRIC SIDE EFFECTS EMERGE DURING ANTIVIRAL TREATMENT OF HEPATITIS C?", Psychiatria Danubina, vol.25, br. 4, str. 0-400, 2013. [Online]. Dostupno na: https://hrcak.srce.hr/162116. [Citirano: 24.10.2020.]

Sažetak
Background: This retrospective study aimed to determine the time-frame regarding the first appearance of psychiatric side
effects in the course of antiviral treatment and the subsequent referral to consultation-liaison psychiatric services.
Subjects and methods: Medical records of patients receiving combined antiviral treatment with alpha interferon and ribavirin
for hepatitis C at a hepatology outpatient clinic and referred to psychiatric consultation between April 2000 and July 2011 were
scrutinized.
Results: Time between the initiation of antiviral treatment and the first appearance of psychiatric symptoms was 10.64±10.68
weeks. Patients were referred to psychiatric examination 16.1±12.7 weeks after antiviral treatment had been commenced. The time
frame of the emergence of psychiatric symptoms and the referral for psychiatric consultation did not correlate with the patients’ age
or sex. No relationship between substance/alcohol abuse and psychiatric history and the timing of psychiatric side effects and their
assessment were found.
Conclusions: This study confirmed that psychiatric side effects appear late in the course of combined antiviral treatment arising
after 10.64±10.68 weeks the treatment started. The results also showed that some patients’ psychiatric symptoms appeared
immediately after the beginning of the antiviral therapy. This finding underlines the importance of monitoring patients’ psychiatric
condition as soon as antiviral treatment commences.

Ključne riječi
hepatitis C - antiviral treatment - psychiatric side effects - substance/alcohol abuse - depression

Hrčak ID: 162116

URI
https://hrcak.srce.hr/162116

Posjeta: 174 *