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Results of the Determination of Serum Markers in Patients with Malignant Melanoma

Liborija Lugović
Mirna Šitum
Marija Buljan
Sanja Poduje
Klaudija Šebetić

Puni tekst: engleski, pdf (153 KB) str. 0-0 preuzimanja: 503* citiraj
APA 6th Edition
Lugović, L., Šitum, M., Buljan, M., Poduje, S. i Šebetić, K. (2007). Results of the Determination of Serum Markers in Patients with Malignant Melanoma. Collegium antropologicum, 31 - Supplement 1 (1), 0-0. Preuzeto s https://hrcak.srce.hr/16382
MLA 8th Edition
Lugović, Liborija, et al. "Results of the Determination of Serum Markers in Patients with Malignant Melanoma." Collegium antropologicum, vol. 31 - Supplement 1, br. 1, 2007, str. 0-0. https://hrcak.srce.hr/16382. Citirano 18.10.2019.
Chicago 17th Edition
Lugović, Liborija, Mirna Šitum, Marija Buljan, Sanja Poduje i Klaudija Šebetić. "Results of the Determination of Serum Markers in Patients with Malignant Melanoma." Collegium antropologicum 31 - Supplement 1, br. 1 (2007): 0-0. https://hrcak.srce.hr/16382
Harvard
Lugović, L., et al. (2007). 'Results of the Determination of Serum Markers in Patients with Malignant Melanoma', Collegium antropologicum, 31 - Supplement 1(1), str. 0-0. Preuzeto s: https://hrcak.srce.hr/16382 (Datum pristupa: 18.10.2019.)
Vancouver
Lugović L, Šitum M, Buljan M, Poduje S, Šebetić K. Results of the Determination of Serum Markers in Patients with Malignant Melanoma. Collegium antropologicum [Internet]. 2007 [pristupljeno 18.10.2019.];31 - Supplement 1(1):0-0. Dostupno na: https://hrcak.srce.hr/16382
IEEE
L. Lugović, M. Šitum, M. Buljan, S. Poduje i K. Šebetić, "Results of the Determination of Serum Markers in Patients with Malignant Melanoma", Collegium antropologicum, vol.31 - Supplement 1, br. 1, str. 0-0, 2007. [Online]. Dostupno na: https://hrcak.srce.hr/16382. [Citirano: 18.10.2019.]

Sažetak
Although there is no routine procedure for determination of serum markers in patients with malignant melanoma
(MM), some markers are being studied as potentially useful prognostic tools. Serum lactate dehydrogenase (LDH), protein
S-100B, melanoma-inhibiting activity (MIA) and tyrosinase may correlate with melanoma progression. In this
study, the results of determination of S100 protein, LDH, MIA and tyrosinase in the serum of 50 patients with MM
(stages I-IV) were determined. The increased values of MIA were found in 26% patients in stage I, while in 50% patients
in stage IV. Increased S-100 protein was found in 13% patients in stage I while in 50% patients in stage IV. The increased
values of LDH were found in 26% patients in stage I, while in 25% patients in stage IV. The positive serum tyrosinase was
noticed in 17.3% patients in stage II, while in 25% patients in stage IV. The obtained results have revealed no significant
differences between the groups in higher and lower stages of the disease, indicating that blood markers are not reliable
prognostic factors for MM progression.

Ključne riječi
malignant melanoma; markers; lactate dehydrogenase (LDH); protein S-100; melanoma-inhibiting activity (MIA); tyrosinase

Hrčak ID: 16382

URI
https://hrcak.srce.hr/16382

Posjeta: 789 *