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https://doi.org/10.20471/acc.2017.56.03.08

Measurable and Unmeasurable Features of Ultrasound Lymph Node Images in Detection of Malignant Infiltration

Tatjana Rotim   ORCID icon orcid.org/0000-0003-0866-0129 ; Department of Diagnostic and Interventional Radiology, Osijek, Croatia
Branka Kristek ; Department of Diagnostic and Interventional Radiology, Osijek, Croatia
Tajana Turk   ORCID icon orcid.org/0000-0003-1535-1359 ; Department of Diagnostic and Interventional Radiology, Osijek, Croatia
Domagoj Kretić   ORCID icon orcid.org/0000-0003-0279-0651 ; Department of Diagnostic and Interventional Radiology, Osijek, Croatia
Marija Perić ; Department of Clinical Cytology, Osijek University Hospital Center, Osijek, Croatia
Ivo Pušeljić ; Department of Diagnostic and Interventional Radiology, Osijek, Croatia
Tijana Pandurović   ORCID icon orcid.org/0000-0002-6670-804X ; Department of Diagnostic and Interventional Radiology, Osijek, Croatia
Mario Štefanić ; 3Department of Nuclear Medicine and Oncology, School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia

Puni tekst: engleski, pdf (113 KB) str. 415-424 preuzimanja: 608* citiraj
APA 6th Edition
Rotim, T., Kristek, B., Turk, T., Kretić, D., Perić, M., Pušeljić, I., ... Štefanić, M. (2017). Measurable and Unmeasurable Features of Ultrasound Lymph Node Images in Detection of Malignant Infiltration. Acta clinica Croatica, 56. (3.), 415-424. https://doi.org/10.20471/acc.2017.56.03.08
MLA 8th Edition
Rotim, Tatjana, et al. "Measurable and Unmeasurable Features of Ultrasound Lymph Node Images in Detection of Malignant Infiltration." Acta clinica Croatica, vol. 56., br. 3., 2017, str. 415-424. https://doi.org/10.20471/acc.2017.56.03.08. Citirano 16.06.2021.
Chicago 17th Edition
Rotim, Tatjana, Branka Kristek, Tajana Turk, Domagoj Kretić, Marija Perić, Ivo Pušeljić, Tijana Pandurović i Mario Štefanić. "Measurable and Unmeasurable Features of Ultrasound Lymph Node Images in Detection of Malignant Infiltration." Acta clinica Croatica 56., br. 3. (2017): 415-424. https://doi.org/10.20471/acc.2017.56.03.08
Harvard
Rotim, T., et al. (2017). 'Measurable and Unmeasurable Features of Ultrasound Lymph Node Images in Detection of Malignant Infiltration', Acta clinica Croatica, 56.(3.), str. 415-424. https://doi.org/10.20471/acc.2017.56.03.08
Vancouver
Rotim T, Kristek B, Turk T, Kretić D, Perić M, Pušeljić I i sur. Measurable and Unmeasurable Features of Ultrasound Lymph Node Images in Detection of Malignant Infiltration. Acta clinica Croatica [Internet]. 2017 [pristupljeno 16.06.2021.];56.(3.):415-424. https://doi.org/10.20471/acc.2017.56.03.08
IEEE
T. Rotim, et al., "Measurable and Unmeasurable Features of Ultrasound Lymph Node Images in Detection of Malignant Infiltration", Acta clinica Croatica, vol.56., br. 3., str. 415-424, 2017. [Online]. https://doi.org/10.20471/acc.2017.56.03.08

Sažetak
The aim of the study was to assess diagnostic value and utility of selected morphological features in predicting lymph node (LN) malignancy using B-mode, Doppler ultrasonography and multivariate settings in a tertiary radiological referral center. The study included 123 patients having undergone ultrasound-guided fine-needle aspiration and cytologic analysis (FNAC) of cervical, axillary and inguinal LNs. Each LN was characterized by long/L and short/T-axis, shape, margins, echogenicity, cortical thickness, vascularization, and examiner’s subjective impression. Within the limitations of FNAC, altered shape and vascularization had relatively high specificity and positive predictive value (>80%), whereas subjective impression had high sensitivity and negative predictive value (100%) for malignancy. The cut-off levels for different features of LN by ROC analysis were as follows: long-axis 23 mm, short-axis 11 mm, L/T ratio 2.19, and maximal cortical thickness 5.1 mm. On multivariate analysis (adaptive regression splines, n=108), the addition of long-axis, L/T ratio, age and sex considerably improved diagnostic accuracy (88%), sensitivity (margins + vascularization) and specificity (subjective impression) of the diagnostic model. The combination of morphological and demographic features could improve diagnostic accuracy, usually with a trade-off between the sensitivity and specificity of the predictive model. The performance may depend on the level of expertise and institutional settings.

Ključne riječi
Lymph nodes – abnormalities; Ultrasonography, doppler; Biopsy, fine-needle; Cytodiagnosis; Predictive value of tests; Croatia

Hrčak ID: 191369

URI
https://hrcak.srce.hr/191369

[hrvatski]

Posjeta: 993 *