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The specific immunological reactivity in breast cancer patients

Damir Eljuga
Josip Fajdić
Ljerka Eljuga
Marica Vrdoljak

Sažetak

We used the leukocyte adherence inhibition (LAI) assay in detecting the specific immune reactivity and monitoring of the dynamics of this immunity in 58 breast cancer patients. We wanted to find out if the level of preoperative specific immune reactivity is in correlation with the survival rate. Soluble antigenic preparations from a breast cancer, rectal carcinoma and fibroadenoma were obtained with 3M KCI. 72% of breast cancer patients showed the specific reactivity to the allogeneic KCI extract from reast carcinoma. Stage II and III patients react better than stage I patients (82% versus 50%). The specific reactivity after surgery and postoperative radiotherapy decreased in stage II and III patients. The reactivity in stage I patients was at the same level during six months. The LAI reacitivity prior to surgery correlates with significantly higher 6-years survival rate.

Ključne riječi

immunological reactivity; LAI assay; breast cancer

Hrčak ID:

194004

URI

https://hrcak.srce.hr/194004

Datum izdavanja:

1.12.1993.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.373 *