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Pregledni rad
https://doi.org/10.5599/admet.532

Block relevance (BR) analysis and polarity descriptors in property-based drug design

Giuseppe Ermondi ; Molecular Biotechnology and Health Sciences Dept., Università degli Studi di Torino, via Quarello 15, 10135 Torino, Italy
Giulia Caron ; Molecular Biotechnology and Health Sciences Dept., Università degli Studi di Torino, via Quarello 15, 10135 Torino, Italy

Puni tekst: engleski, pdf (1 MB) str. 215-224 preuzimanja: 155* citiraj
APA 6th Edition
Ermondi, G. i Caron, G. (2018). Block relevance (BR) analysis and polarity descriptors in property-based drug design. ADMET and DMPK, 6 (3), 215-224. https://doi.org/10.5599/admet.532
MLA 8th Edition
Ermondi, Giuseppe i Giulia Caron. "Block relevance (BR) analysis and polarity descriptors in property-based drug design." ADMET and DMPK, vol. 6, br. 3, 2018, str. 215-224. https://doi.org/10.5599/admet.532. Citirano 18.11.2019.
Chicago 17th Edition
Ermondi, Giuseppe i Giulia Caron. "Block relevance (BR) analysis and polarity descriptors in property-based drug design." ADMET and DMPK 6, br. 3 (2018): 215-224. https://doi.org/10.5599/admet.532
Harvard
Ermondi, G., i Caron, G. (2018). 'Block relevance (BR) analysis and polarity descriptors in property-based drug design', ADMET and DMPK, 6(3), str. 215-224. https://doi.org/10.5599/admet.532
Vancouver
Ermondi G, Caron G. Block relevance (BR) analysis and polarity descriptors in property-based drug design. ADMET and DMPK [Internet]. 2018 [pristupljeno 18.11.2019.];6(3):215-224. https://doi.org/10.5599/admet.532
IEEE
G. Ermondi i G. Caron, "Block relevance (BR) analysis and polarity descriptors in property-based drug design", ADMET and DMPK, vol.6, br. 3, str. 215-224, 2018. [Online]. https://doi.org/10.5599/admet.532

Sažetak
Block Relevance (BR) analysis is a tool to interpret QSPR/PLS models which can provide the information content of any physicochemical determinant used in property-based drug discovery; its application for the characterization of experimental polarity descriptors is discussed.

Ključne riječi
ADME; hydrogen bonding; IAM; QSPR; PLS; PSA; VIP

Hrčak ID: 205903

URI
https://hrcak.srce.hr/205903

Posjeta: 231 *