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Izvorni znanstveni članak
https://doi.org/10.20471/acc.2018.57.02.04

Expression of NEDD9 in Transbronchial Biopsies of Lung Adenocarcinoma

Jelena Ostojić   ORCID icon orcid.org/0000-0002-0314-331X ; Special Hospital for Pulmonary Diseases, Zagreb, Croatia
Luka Brčić ; Medical University of Graz, Institute of Pathology, Graz, Austria
Pero Hrabač ; School of Medicine, University of Zagreb, Croatian Institute for Brain Research, Zagreb, Croatia
Sven Seiwerth ; School of Medicine, University of Zagreb, Zagreb, Croatia; Institute of Pathology and Zagreb University Hospital Centre, Clinical Department of Pathology, Zagreb, Croatia

Puni tekst: engleski, pdf (863 KB) str. 251-256 preuzimanja: 107* citiraj
APA 6th Edition
Ostojić, J., Brčić, L., Hrabač, P. i Seiwerth, S. (2018). Expression of NEDD9 in Transbronchial Biopsies of Lung Adenocarcinoma. Acta clinica Croatica, 57 (2), 251-256. https://doi.org/10.20471/acc.2018.57.02.04
MLA 8th Edition
Ostojić, Jelena, et al. "Expression of NEDD9 in Transbronchial Biopsies of Lung Adenocarcinoma." Acta clinica Croatica, vol. 57, br. 2, 2018, str. 251-256. https://doi.org/10.20471/acc.2018.57.02.04. Citirano 25.08.2019.
Chicago 17th Edition
Ostojić, Jelena, Luka Brčić, Pero Hrabač i Sven Seiwerth. "Expression of NEDD9 in Transbronchial Biopsies of Lung Adenocarcinoma." Acta clinica Croatica 57, br. 2 (2018): 251-256. https://doi.org/10.20471/acc.2018.57.02.04
Harvard
Ostojić, J., et al. (2018). 'Expression of NEDD9 in Transbronchial Biopsies of Lung Adenocarcinoma', Acta clinica Croatica, 57(2), str. 251-256. https://doi.org/10.20471/acc.2018.57.02.04
Vancouver
Ostojić J, Brčić L, Hrabač P, Seiwerth S. Expression of NEDD9 in Transbronchial Biopsies of Lung Adenocarcinoma. Acta clinica Croatica [Internet]. 2018 [pristupljeno 25.08.2019.];57(2):251-256. https://doi.org/10.20471/acc.2018.57.02.04
IEEE
J. Ostojić, L. Brčić, P. Hrabač i S. Seiwerth, "Expression of NEDD9 in Transbronchial Biopsies of Lung Adenocarcinoma", Acta clinica Croatica, vol.57, br. 2, str. 251-256, 2018. [Online]. https://doi.org/10.20471/acc.2018.57.02.04

Sažetak
Lung cancer as the major cause of cancer mortality worldwide includes several histologic subtypes evolving from numerous genetic and epigenetic changes emerging in alveolar, bronchiolar and bronchial epithelium. Th e majority of cases are diagnosed in advanced stage (i.e. stages IIIB and IV), often with scanty amount of tissue in transbronchial biopsies or cytology specimens. Th e aim of the present study was to investigate the expression of the scaff olding protein neural precursor cell expressed, developmentally downregulated 9 (NEDD9) in small biopsies of lung adenocarcinoma. The expression of NEDD9 was analyzed immunohistochemically in 71 formalin-fi xed and paraffin-embedded transbronchial biopsy specimens of primary lung adenocarcinoma. Nuclear and cytoplasmic NEDD9 expression was detected indicating activation of the epithelial-mesenchymal transition process. Direct relationship between the expression of NEDD9 and survival was not
demonstrated.

Ključne riječi
Lung Neoplasms; Adenocarcinoma; Biopsy, Needle; Adaptor Proteins, Signal Transducing; Croatia

Hrčak ID: 207506

URI
https://hrcak.srce.hr/207506

[hrvatski]

Posjeta: 216 *