Pregledni rad
Psychopharmaca in Pregnancy
Nada John
Ivana Bakija
Dražen Begić
Srećko Ciglar
Vera Folnegović Šmalc
Sažetak
Pregnancy is a special period in the life of a
woman, in which numerous physiological functions are
changed and become specific for pregnancy. Due to this fact,
the pharmacokynetics of some drugs is being changed.
Besides, during pregnancy the majority of drugs enter fetal
metabolism, often in different concentrations than in the
mother’s bloodflow. Thus special attention should be devoted
to possible untoward impact of psychopharmaca on the
fetus. Pregnancy is the period in which mental disorders often
start, a series of earlier disorders continue, relapse of a certain
mental disorder can occur, so pregnancy might start in
the phase of maintenance therapy or prevention of relapse. All
this in a way indicates the application of psychopharmaca.
Furthermore, the obstetric practice itself often applies psychopharmaca,
particularly anxiolytics, either because of their
anxiolytic activity or because of their myorelaxant action with
the aim of preventing contractions. With regard to the mentioned
facts, in clinical practise often emerges a dilemma how
much is the application of psychopharmaca in pregnancy and
lactation justified, as well as in the period of planning a pregnancy.
The question is whether we harm more by applying psychopharmaca
with increasing the risk of possible side effects
in the child or the determination of mother’s mental condition
is a greater danger both for the mother herself and for the
child. The choice of treatment methods should always be
determined with maximal individual approach and with preference
of methods and drugs with the lowest risk of harm for
the child and the mother.
Ključne riječi
pregnancy; lactation; pregnancy planning; risk factors; FDA recomendations
Hrčak ID:
20023
URI
Datum izdavanja:
25.9.2002.
Posjeta: 2.196 *