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Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia

Branislav Lekić
Mirjana Gajić-Veljić
Branka Bonači-Nikolić
Miloš Nikolić ; Department of DermatovenereologyFaculty of Medicine, University of BelgradePasterova 211000 BelgradeSerbia

Puni tekst: engleski, PDF (184 KB) str. 28-28 preuzimanja: 175* citiraj
APA 6th Edition
Lekić, B., Gajić-Veljić, M., Bonači-Nikolić, B. i Nikolić, M. (2019). Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia. Acta Dermatovenerologica Croatica, 27 (1), 28-28. Preuzeto s https://hrcak.srce.hr/219586
MLA 8th Edition
Lekić, Branislav, et al. "Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia." Acta Dermatovenerologica Croatica, vol. 27, br. 1, 2019, str. 28-28. https://hrcak.srce.hr/219586. Citirano 28.11.2021.
Chicago 17th Edition
Lekić, Branislav, Mirjana Gajić-Veljić, Branka Bonači-Nikolić i Miloš Nikolić. "Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia." Acta Dermatovenerologica Croatica 27, br. 1 (2019): 28-28. https://hrcak.srce.hr/219586
Harvard
Lekić, B., et al. (2019). 'Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia', Acta Dermatovenerologica Croatica, 27(1), str. 28-28. Preuzeto s: https://hrcak.srce.hr/219586 (Datum pristupa: 28.11.2021.)
Vancouver
Lekić B, Gajić-Veljić M, Bonači-Nikolić B, Nikolić M. Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia. Acta Dermatovenerol Croat. [Internet]. 2019 [pristupljeno 28.11.2021.];27(1):28-28. Dostupno na: https://hrcak.srce.hr/219586
IEEE
B. Lekić, M. Gajić-Veljić, B. Bonači-Nikolić i M. Nikolić, "Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia", Acta Dermatovenerologica Croatica, vol.27, br. 1, str. 28-28, 2019. [Online]. Dostupno na: https://hrcak.srce.hr/219586. [Citirano: 28.11.2021.]

Sažetak

Cutaneous necrotizing eosinophilic vasculitis (CNEV) is a rare type of vasculitis. Eosinophilic vasculitis is a necrotizing vasculitis with eosinophilic vascular infiltration, in which eosinophils mediate vascular damage in the disease process. We present a case of an 18-year-old girl who developed palpable purpura and hemorrhagic bullae over the lower extremities associated with itching, 7 days after the commencement of penicillin therapy. Plasma cryofibrinogen was positive. Histopathology showed an infiltration of eosinophils within and around the vessel walls and a complete absence of nuclear dust and neutrophils. Oral prednisone at 1 mg/kg induced remission in 2 weeks; the prednisone dose was tapered and discontinued after 2.5 months. There was no evidence of recurrence after 37 months of follow-up. Our patient represents a rare case of drug/penicillin-induced CNEV associated with cryofibrinogenemia, without systemic organ involvement.

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Hrčak ID: 219586

URI
https://hrcak.srce.hr/219586

Posjeta: 331 *