Medica Jadertina, Vol. 38 No. 1-2, 2008.
Izvorni znanstveni članak
The frequency of most common organisms causing urinary tract infection in pediatric patients and their susceptibility to antimicrobial drugs
Carmen Prohaska-Potočnik
; Zavod za mikrobiologiju, parazitologiju i bolničke infekcije, KB Sestre milosrdnice, Zagreb
Marija Vesna Vukadinović
; Zavod za mikrobiologiju, parazitologiju i bolničke infekcije, KB
Haris Car
; Zavod za mikrobiologiju, parazitologiju i bolničke infekcije, KB
Sažetak
After respiratory infections, urinary tract infections (UTI) are most common in pediatric patients. In young children, UTI is a marker for urinary tract abnormalities and in the newborn it may be associated with bacteraemia. In infants/early school age children it may lead to renal scarring, hypertension and rarely to the end stage renal failure.
The aim of the present study was to identify the most common bacteria, causative agents of UTI in urine of pediatric patients, as well as their susceptibility to antimicrobial drugs commonly used for UTI prevention and treatment in children.
Urine cultures were seeded (inoculated), 0,01 ml of undiluted urine samples, with calibrated pipette on standard nutrient media. In urine cultures with signifficant bacterial count, Escherichia coli was the most
common organism isolated (71%), followed by Proteus mirabilis (11%), Klebsiella pneumoniae (7%), Enterococcus (7%), Pseudomonas (2%) and Morganella morganii (2%). Proteus is more often found in boys (9/15) and Klebsiella in girls (7/9) .Resistance against ampicillin in isolated E. coli strains were 70% against otrimoxasol 30% . Their use in empirical treatment is inadequate. In the investigated samples 13% ESBL-positive strains of E. coli were
found, 9/12 in boys, 6/9 during the first month of life.
To evaluate the options for empirical treatment, permanent follow up of sensitivity/resistance pattern in the most commonly isolated causative agents of UTI in pediatric patients is recommended.
Ključne riječi
Urinary tract infection (UTI); children; Antibiotic resistance; Escherichia coli
Hrčak ID:
22671
URI
Datum izdavanja:
5.5.2008.
Posjeta: 6.098 *