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Serum and Tissue Angiotensin Converting Enzyme in Patients with Psoriasis

Jasminko Huskić
Nedžad Mulabegović
Faruk Alendar
Ljerka Ostojić
Zdenko Ostojić
Dubravka Šimić
Ruža Miličević
Mladenka Naletilić

Puni tekst: engleski, pdf (66 KB) str. 1215-1219 preuzimanja: 374* citiraj
APA 6th Edition
Huskić, J., Mulabegović, N., Alendar, F., Ostojić, Lj., Ostojić, Z., Šimić, D., ... Naletilić, M. (2008). Serum and Tissue Angiotensin Converting Enzyme in Patients with Psoriasis. Collegium antropologicum, 32 (4), 1215-1219. Preuzeto s https://hrcak.srce.hr/34308
MLA 8th Edition
Huskić, Jasminko, et al. "Serum and Tissue Angiotensin Converting Enzyme in Patients with Psoriasis." Collegium antropologicum, vol. 32, br. 4, 2008, str. 1215-1219. https://hrcak.srce.hr/34308. Citirano 26.09.2020.
Chicago 17th Edition
Huskić, Jasminko, Nedžad Mulabegović, Faruk Alendar, Ljerka Ostojić, Zdenko Ostojić, Dubravka Šimić, Ruža Miličević i Mladenka Naletilić. "Serum and Tissue Angiotensin Converting Enzyme in Patients with Psoriasis." Collegium antropologicum 32, br. 4 (2008): 1215-1219. https://hrcak.srce.hr/34308
Harvard
Huskić, J., et al. (2008). 'Serum and Tissue Angiotensin Converting Enzyme in Patients with Psoriasis', Collegium antropologicum, 32(4), str. 1215-1219. Preuzeto s: https://hrcak.srce.hr/34308 (Datum pristupa: 26.09.2020.)
Vancouver
Huskić J, Mulabegović N, Alendar F, Ostojić Lj, Ostojić Z, Šimić D i sur. Serum and Tissue Angiotensin Converting Enzyme in Patients with Psoriasis. Collegium antropologicum [Internet]. 2008 [pristupljeno 26.09.2020.];32(4):1215-1219. Dostupno na: https://hrcak.srce.hr/34308
IEEE
J. Huskić, et al., "Serum and Tissue Angiotensin Converting Enzyme in Patients with Psoriasis", Collegium antropologicum, vol.32, br. 4, str. 1215-1219, 2008. [Online]. Dostupno na: https://hrcak.srce.hr/34308. [Citirano: 26.09.2020.]

Sažetak
Recent evidence suggests that the angiotensin converting enzyme (ACE) is present in skin. The real value of the determination
of ACE activity as a clinical-biochemistry test for the diagnosis of psoriasis has not been attained. Serum and
tissue ACE were measured in 60 patients with psoriasis, 20 patients with lichen planus, 20 patients with seborrhoic dermatitis
and in 20 healthy individuals. The serum and tissue ACE activity was determined before and after therapy, using
the spectrophotometric method and hippuryl-l-histidyl-l-leucine as a substrate. The results showed that serum ACE
activity before therapy was significantly increased in both groups – patients with psoriasis (p<0.001) and patients with
lichen planus (p<0,001) in comparison to healthy individuals. However, there were no significant differences in serum
ACE activity among patients with seborrhoic dermatitis and healthy individuals. After therapy, serum ACE activity significantly
decreased in both groups of patients with psoriasis and patients with lichen planus comparing it to the level
found in the control group. The values in both were similar. The tissue ACE activity in altered skin was significantly increased
only in the patients with psoriasis in comparison to uninvolved skin of these patients, as well as the skin of
healthy individuals. After therapy, there were no significant differences in tissue ACE activity between the treated skin
and the healthy skin. In conclusion, determination of tissue angiotensin converting enzyme activity can be used in the
differential diagnostic of indistinct clinical forms of psoriasis.

Ključne riječi
angiotensin converting enzyme; psoriasis; serum; tissue

Hrčak ID: 34308

URI
https://hrcak.srce.hr/34308

Posjeta: 561 *