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Prevalence of Bisphosphonate Associated Osteonecrosis of the Jaws in Breast Cancer Patients

Christian Walter ; Klinik für Mund- Kiefer- und Gesichtschirurgie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Germany
Knut A. Grötz ; Klinik für Mund- Kiefer- und Gesichtschirurgie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz; Klinik für Mund-Kiefer-Gesichtschirurgie, der HSK Dr. Horst Schmidt Klinik, Wiesbaden, Germany
Adrian Kašaj ; Poliklinik für Zahnerhaltungskunde, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Germany
Stefan Albricht ; Klinik und Poliklinik für Geburtshilfe und Frauenheilkunde, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Germany
Marcus Schmidt ; Klinik und Poliklinik für Geburtshilfe und Frauenheilkunde, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Germany
Bastian Nauroth ; Klinik für Mund- Kiefer- und Gesichtschirurgie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Germany
Bilal Al-Nawas ; Klinik für Mund- Kiefer- und Gesichtschirurgie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, Germany

Puni tekst: engleski, pdf (334 KB) str. 271-278 preuzimanja: 696* citiraj
APA 6th Edition
Walter, C., Grötz, K.A., Kašaj, A., Albricht, S., Schmidt, M., Nauroth, B. i Al-Nawas, B. (2009). Prevalence of Bisphosphonate Associated Osteonecrosis of the Jaws in Breast Cancer Patients. Acta stomatologica Croatica, 43 (4), 271-278. Preuzeto s https://hrcak.srce.hr/44905
MLA 8th Edition
Walter, Christian, et al. "Prevalence of Bisphosphonate Associated Osteonecrosis of the Jaws in Breast Cancer Patients." Acta stomatologica Croatica, vol. 43, br. 4, 2009, str. 271-278. https://hrcak.srce.hr/44905. Citirano 30.09.2020.
Chicago 17th Edition
Walter, Christian, Knut A. Grötz, Adrian Kašaj, Stefan Albricht, Marcus Schmidt, Bastian Nauroth i Bilal Al-Nawas. "Prevalence of Bisphosphonate Associated Osteonecrosis of the Jaws in Breast Cancer Patients." Acta stomatologica Croatica 43, br. 4 (2009): 271-278. https://hrcak.srce.hr/44905
Harvard
Walter, C., et al. (2009). 'Prevalence of Bisphosphonate Associated Osteonecrosis of the Jaws in Breast Cancer Patients', Acta stomatologica Croatica, 43(4), str. 271-278. Preuzeto s: https://hrcak.srce.hr/44905 (Datum pristupa: 30.09.2020.)
Vancouver
Walter C, Grötz KA, Kašaj A, Albricht S, Schmidt M, Nauroth B i sur. Prevalence of Bisphosphonate Associated Osteonecrosis of the Jaws in Breast Cancer Patients. Acta stomatologica Croatica [Internet]. 2009 [pristupljeno 30.09.2020.];43(4):271-278. Dostupno na: https://hrcak.srce.hr/44905
IEEE
C. Walter, et al., "Prevalence of Bisphosphonate Associated Osteonecrosis of the Jaws in Breast Cancer Patients", Acta stomatologica Croatica, vol.43, br. 4, str. 271-278, 2009. [Online]. Dostupno na: https://hrcak.srce.hr/44905. [Citirano: 30.09.2020.]
Puni tekst: hrvatski, pdf (334 KB) str. 271-278 preuzimanja: 365* citiraj
APA 6th Edition
Walter, C., Grötz, K.A., Kašaj, A., Albricht, S., Schmidt, M., Nauroth, B. i Al-Nawas, B. (2009). Prevalencija osteonekroze čeljusti povezane s bisfosfonatima kod pacijenata s rakom dojke. Acta stomatologica Croatica, 43 (4), 271-278. Preuzeto s https://hrcak.srce.hr/44905
MLA 8th Edition
Walter, Christian, et al. "Prevalencija osteonekroze čeljusti povezane s bisfosfonatima kod pacijenata s rakom dojke." Acta stomatologica Croatica, vol. 43, br. 4, 2009, str. 271-278. https://hrcak.srce.hr/44905. Citirano 30.09.2020.
Chicago 17th Edition
Walter, Christian, Knut A. Grötz, Adrian Kašaj, Stefan Albricht, Marcus Schmidt, Bastian Nauroth i Bilal Al-Nawas. "Prevalencija osteonekroze čeljusti povezane s bisfosfonatima kod pacijenata s rakom dojke." Acta stomatologica Croatica 43, br. 4 (2009): 271-278. https://hrcak.srce.hr/44905
Harvard
Walter, C., et al. (2009). 'Prevalencija osteonekroze čeljusti povezane s bisfosfonatima kod pacijenata s rakom dojke', Acta stomatologica Croatica, 43(4), str. 271-278. Preuzeto s: https://hrcak.srce.hr/44905 (Datum pristupa: 30.09.2020.)
Vancouver
Walter C, Grötz KA, Kašaj A, Albricht S, Schmidt M, Nauroth B i sur. Prevalencija osteonekroze čeljusti povezane s bisfosfonatima kod pacijenata s rakom dojke. Acta stomatologica Croatica [Internet]. 2009 [pristupljeno 30.09.2020.];43(4):271-278. Dostupno na: https://hrcak.srce.hr/44905
IEEE
C. Walter, et al., "Prevalencija osteonekroze čeljusti povezane s bisfosfonatima kod pacijenata s rakom dojke", Acta stomatologica Croatica, vol.43, br. 4, str. 271-278, 2009. [Online]. Dostupno na: https://hrcak.srce.hr/44905. [Citirano: 30.09.2020.]

Sažetak
Objective: To evaluate the prevalence of Bisphosphonate-associated-osteonecrosis-of-the-jaws (BP-ONJ) and protective factors of BP-ONJ-development in breast cancer patients with osseous metastasis and bisphosphonate therapy using systematical dental oral examinations. Material and Methods: A cross-sectional-study was conducted in the Department for Gynecology in Mainz, Germany. All breast cancer patients (n=51) treated with bisphosphonate in the time span from 07/2006 to 09/2007 were recruited. Primary outcome was the development of BP-ONJ and the detection of possible additional trigger factors for the development of BP-ONJ, as well as possible factors for avoiding BP-ONJ. Results: Only 1 out of 51 patients developed BP-ONJ (2.0%). A tooth extraction could be identified as an additional trigger factor. The overall dental hygiene of this patient clientele was above average. Conclusion: Compared to other alignant diseases, BP-ONJ in breast cancer patients does not appear as often. The underlying disease might be of importance in the development of BP-ONJ. A good dental hygiene might be a protective factor.

Ključne riječi
Bisphosphonates; Osteonecrosis; Jaw diseases; Breast cancer; Oral hygiene

Hrčak ID: 44905

URI
https://hrcak.srce.hr/44905

[hrvatski]

Posjeta: 1.634 *