hrcak mascot   Srce   HID

Pregledni rad

The Role of Oxygen in Cardiac Arrest Resuscitation

Mark G. Angelos ; The Ohio State University, 1654 Upham Drive, Columbus, OH 43210

Puni tekst: engleski, pdf (98 KB) str. 28-31 preuzimanja: 331* citiraj
APA 6th Edition
Angelos, M.G. (2010). The Role of Oxygen in Cardiac Arrest Resuscitation. Signa vitae, 5 (Suppl. 1), 28-31. Preuzeto s https://hrcak.srce.hr/59433
MLA 8th Edition
Angelos, Mark G.. "The Role of Oxygen in Cardiac Arrest Resuscitation." Signa vitae, vol. 5, br. Suppl. 1, 2010, str. 28-31. https://hrcak.srce.hr/59433. Citirano 30.03.2020.
Chicago 17th Edition
Angelos, Mark G.. "The Role of Oxygen in Cardiac Arrest Resuscitation." Signa vitae 5, br. Suppl. 1 (2010): 28-31. https://hrcak.srce.hr/59433
Harvard
Angelos, M.G. (2010). 'The Role of Oxygen in Cardiac Arrest Resuscitation', Signa vitae, 5(Suppl. 1), str. 28-31. Preuzeto s: https://hrcak.srce.hr/59433 (Datum pristupa: 30.03.2020.)
Vancouver
Angelos MG. The Role of Oxygen in Cardiac Arrest Resuscitation. Signa vitae [Internet]. 2010 [pristupljeno 30.03.2020.];5(Suppl. 1):28-31. Dostupno na: https://hrcak.srce.hr/59433
IEEE
M.G. Angelos, "The Role of Oxygen in Cardiac Arrest Resuscitation", Signa vitae, vol.5, br. Suppl. 1, str. 28-31, 2010. [Online]. Dostupno na: https://hrcak.srce.hr/59433. [Citirano: 30.03.2020.]

Sažetak
The heart is incapable of storing significant oxygen or substrates and thus is entirely dependent on a continuous delivery
of flow in order to support its high metabolic state. Following cardiac arrest, myocardial tissue oxygen tension falls rapidly
and aerobic production of ATP ceases. Without re-oxygenation of the ischemic myocardium, return of spontaneous circulation
(ROSC) cannot be achieved. The oxygen paradox which has been described regarding other ischemia-reperfusion
conditions seems to have application in cardiac arrest. It is clear that some level of oxygenation is necessary to achieve
ROSC, however post ROSC there appears to be increased toxicity associated with hyperoxia. The optimal conditions for
re-oxygenation in the setting of cardiac arrest remain ill defined at present.

Ključne riječi
cardiac arrest; oxygen; myocard; oxygen delivery; Adenosine- 5'-triphosphate (ATP); mitochondria; measurement of tissue oxygen; oxygen paradox

Hrčak ID: 59433

URI
https://hrcak.srce.hr/59433

Posjeta: 480 *