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Real-Time Expression of hTERT in Primary Melanoma Biopsies

Miljenko Katunarić
Davor Jurišić
Ita Hadžisejdić
Ivan Kirin
Gordana Zamolo

Puni tekst: engleski, pdf (80 KB) str. 1401-1404 preuzimanja: 181* citiraj
APA 6th Edition
Katunarić, M., Jurišić, D., Hadžisejdić, I., Kirin, I. i Zamolo, G. (2010). Real-Time Expression of hTERT in Primary Melanoma Biopsies. Collegium antropologicum, 34 (4), 1401-1404. Preuzeto s https://hrcak.srce.hr/62843
MLA 8th Edition
Katunarić, Miljenko, et al. "Real-Time Expression of hTERT in Primary Melanoma Biopsies." Collegium antropologicum, vol. 34, br. 4, 2010, str. 1401-1404. https://hrcak.srce.hr/62843. Citirano 10.12.2019.
Chicago 17th Edition
Katunarić, Miljenko, Davor Jurišić, Ita Hadžisejdić, Ivan Kirin i Gordana Zamolo. "Real-Time Expression of hTERT in Primary Melanoma Biopsies." Collegium antropologicum 34, br. 4 (2010): 1401-1404. https://hrcak.srce.hr/62843
Harvard
Katunarić, M., et al. (2010). 'Real-Time Expression of hTERT in Primary Melanoma Biopsies', Collegium antropologicum, 34(4), str. 1401-1404. Preuzeto s: https://hrcak.srce.hr/62843 (Datum pristupa: 10.12.2019.)
Vancouver
Katunarić M, Jurišić D, Hadžisejdić I, Kirin I, Zamolo G. Real-Time Expression of hTERT in Primary Melanoma Biopsies. Collegium antropologicum [Internet]. 2010 [pristupljeno 10.12.2019.];34(4):1401-1404. Dostupno na: https://hrcak.srce.hr/62843
IEEE
M. Katunarić, D. Jurišić, I. Hadžisejdić, I. Kirin i G. Zamolo, "Real-Time Expression of hTERT in Primary Melanoma Biopsies", Collegium antropologicum, vol.34, br. 4, str. 1401-1404, 2010. [Online]. Dostupno na: https://hrcak.srce.hr/62843. [Citirano: 10.12.2019.]

Sažetak
Skin melanoma is by far the most lethal skin cancer, it is unpredictable by nature and presents a severe diagnostic problem. One of the major issues in melanoma diagnostics is to differentiate it with confidence from a dysplastic nevus. Thus, the aim of this study was to evaluate hTERT expression on a spectrum of dermal lesions (from normal skin to primary melanoma) in order to examine its possible role as a diagnostic marker in melanoma diagnostics. In this study we analyzed the expression of hTERT by real-time PCR on 58 freshly obtained biopsy samples (4 samples of normal skin, 12 dermal nevi, 23 dysplastic nevi, 19 primary melanomas). Our results showed slightly greater hTERT expression in dysplastic nevi than melanomas with major data overlap. Considering the given results, hTERT does not seem to be a reliable diagnostic marker for melanoma.

Ključne riječi
hTERT; primary melanoma; Real-Time; expression; biopsies

Hrčak ID: 62843

URI
https://hrcak.srce.hr/62843

Posjeta: 331 *