Periodicum biologorum, Vol. 117 No. 2, 2015.
Esej
Functional neuroanatomy of nociception and pain
ANA HLADNIK
; University of Zagreb, School of Medicine, Department of Anatomy and Clinical Anatomy, Croatian Institute for Brain Research, Šalata 11, Zagreb, Croatia
IVANA BIČANIĆ
; University of Zagreb, School of Medicine, Department of Anatomy and Clinical Anatomy, Croatian Institute for Brain Research, Šalata 11, Zagreb, Croatia
ZDRAVKO PETANJEK
; University of Zagreb, School of Medicine, Department of Anatomy and Clinical Anatomy, Croatian Institute for Brain Research, Šalata 11, Zagreb, Croatia
Sažetak
Pain is a complex sensory state based on the integration of a variety of nociceptive inputs processed centrally through many parallel and overlapping neural systems. The traditional anatomical concept implies that nociceptive information is dominantly used to generate and regulate perception of pain through one major sensory pathway. It becomes recognized that experiencing the affective component of the pain is at least as important as perception. Also, nociceptive information is strongly influencing brain centers for regulating
homeostasis. So, understanding neuroanatomical organization of
central processing of nociceptive information is of great clinical importance. There is an attempt to simplify this complex set of interacting networks to a core set of brain regions or a generalizable pain signature. Herewith we wish to give a short overview of recent advances by presenting principles about neuroanatomical organization for processing various aspects of nociceptive
inputs.
Ključne riječi
Hrčak ID:
140409
URI
Datum izdavanja:
10.6.2015.
Posjeta: 4.966 *