Pregledni rad
The Application of Bactericidal Silver Nanoparticles in Wound Treatment
Geewoo Nam
; College of Pharmacy, Seoul National University, Seoul, South Korea
Sabarinathan Rangasamy
; College of Pharmacy, Seoul National University, Seoul, South Korea
Baskaran Purushothaman
; College of Pharmacy, Seoul National University, Seoul, South Korea
Joon Myong Song
; College of Pharmacy, Seoul National University, Seoul, South Korea
Sažetak
Even with the prevalence of wounds, the medical technology for efficiently managing skin damage is still primitive. The disruption of any of the numerous healing processes can lead to problems in the time-sensitive healing actions of the dermal and epidermal layers. Bacterial infection is one of the major obstacles to proper wound healing as it poses a danger of causing long-term negative effects. Keeping the wound free of bacteria is imperative to the proper and hasty repair of dermal wounds. Silver has been widely used to treat wounds for its bactericidal properties. Although the mechanism of silver’s antibacterial action is not fully understood, it exhibits a significant antimicrobial efficacy against a wide spectrum of bacterial species. A number of different approaches to the mechanism are reported and presented in this review. Silver nanoparticles (AgNPs) have been reported to exhibit enhanced antibacterial activity due to their increased surface-area-to-volume ratio. AgNPs are capable of various modifications, significantly broadening the therapeutic properties of the material as a result. This review explores the different aspects of silver and silver nanoparticles, and their antibacterial properties, which can be applied in the field of wound treatments.
Ključne riječi
wound treatment; antibacterial; silver; silver nanoparticles
Hrčak ID:
142587
URI
Datum izdavanja:
1.1.2015.
Posjeta: 2.418 *