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https://doi.org/10.18054/pb.v120i1.6229

A young researcher’s guide to NME/Nm23/NDP Kinase

Maja Herak Bosnar   ORCID icon orcid.org/0000-0002-8448-4713 ; Ruđer Bošković Institute
Martina Radić ; Ruđer Bošković Institute
Helena Ćetković ; Ruđer Bošković Institute

Puni tekst: engleski, PDF (686 KB) str. 3-9 preuzimanja: 515* citiraj
APA 6th Edition
Herak Bosnar, M., Radić, M. i Ćetković, H. (2018). A young researcher’s guide to NME/Nm23/NDP Kinase. Periodicum biologorum, 120 (1), 3-9. https://doi.org/10.18054/pb.v120i1.6229
MLA 8th Edition
Herak Bosnar, Maja, et al. "A young researcher’s guide to NME/Nm23/NDP Kinase." Periodicum biologorum, vol. 120, br. 1, 2018, str. 3-9. https://doi.org/10.18054/pb.v120i1.6229. Citirano 28.09.2020.
Chicago 17th Edition
Herak Bosnar, Maja, Martina Radić i Helena Ćetković. "A young researcher’s guide to NME/Nm23/NDP Kinase." Periodicum biologorum 120, br. 1 (2018): 3-9. https://doi.org/10.18054/pb.v120i1.6229
Harvard
Herak Bosnar, M., Radić, M., i Ćetković, H. (2018). 'A young researcher’s guide to NME/Nm23/NDP Kinase', Periodicum biologorum, 120(1), str. 3-9. https://doi.org/10.18054/pb.v120i1.6229
Vancouver
Herak Bosnar M, Radić M, Ćetković H. A young researcher’s guide to NME/Nm23/NDP Kinase. Periodicum biologorum [Internet]. 2018 [pristupljeno 28.09.2020.];120(1):3-9. https://doi.org/10.18054/pb.v120i1.6229
IEEE
M. Herak Bosnar, M. Radić i H. Ćetković, "A young researcher’s guide to NME/Nm23/NDP Kinase", Periodicum biologorum, vol.120, br. 1, str. 3-9, 2018. [Online]. https://doi.org/10.18054/pb.v120i1.6229

Sažetak

Nucleoside diphosphate kinases (NDPKs) catalyze the exchange of the terminal phosphate from trinucleotides to dinucleotides through a high-energy phosphohistidine intermedier. They are encoded by NME genes and have been found, with a few exceptions, in all living beings. Besides their well-known function as key regulators of the cellular nucleotide homeostasis, they have been appointed numerous additional biochemical and biological functions. The discovery of NME1/NDPK A as the first metastasis suppressor opened new avenues in cancer research. Although the precise role of NME genes/proteins in cancer dissemination is not yet revealed, it seems that further intensive research in this field may lead to new advances in cancer diagnosis and prognosis, as well as encourage new therapeutic strategies.

Hrčak ID: 204224

URI
https://hrcak.srce.hr/204224

Posjeta: 654 *