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https://doi.org/10.2478/aiht-2019-70-3211

Dynamics of exhaled breath temperature after smoking a cigarette and its association with lung function changes predictive of COPD risk in smokers: a cross-sectional study

Ivana Huljev Šipoš ; Department of Pulmonology, General Hospital Šibenik, Šibenik, Croatia
Slavica Labor ; Department of Pulmonology, University Hospital Center Osijek, Osijek, Croatia 3 Faculty of Medicine, J. J. Strossmayer University of Osijek, Osijek, Croatia
Iva Jurić ; Department of Cardiology, University Hospital Center Osijek, Osijek, Croatia
Davor Plavec   ORCID icon orcid.org/0000-0003-2020-8119 ; Faculty of Medicine, J. J. Strossmayer University of Osijek, Osijek, Croatia, 5 Research Department, Srebrnjak Children’s Hospital, Zagreb, Croatia
Kristian Vlahoviček ; Research Department, Srebrnjak Children’s Hospital, Zagreb, Croatia 6 Bioinformatics Group, Division of Molecular Biology, Department of Biology, Faculty of Science, University of Zagreb, Zagreb, Croatia
Siniša Bogović ; Department of Cardiac Surgery, University Hospital Center Osijek, Osijek, Croatia
Justinija Pavkov Vukelić ; Department of Medicine, County General Hospital Našice, Našice, Croatia
Marina Labor ; Department of Pulmonology, University Hospital Center Osijek, Osijek, Croatia 3 Faculty of Medicine, J. J. Strossmayer University of Osijek, Osijek, Croatia

Puni tekst: engleski, pdf (248 KB) str. 123-129 preuzimanja: 198* citiraj
APA 6th Edition
Huljev Šipoš, I., Labor, S., Jurić, I., Plavec, D., Vlahoviček, K., Bogović, S., ... Labor, M. (2019). Dynamics of exhaled breath temperature after smoking a cigarette and its association with lung function changes predictive of COPD risk in smokers: a cross-sectional study. Arhiv za higijenu rada i toksikologiju, 70 (2), 123-129. https://doi.org/10.2478/aiht-2019-70-3211
MLA 8th Edition
Huljev Šipoš, Ivana, et al. "Dynamics of exhaled breath temperature after smoking a cigarette and its association with lung function changes predictive of COPD risk in smokers: a cross-sectional study." Arhiv za higijenu rada i toksikologiju, vol. 70, br. 2, 2019, str. 123-129. https://doi.org/10.2478/aiht-2019-70-3211. Citirano 06.12.2020.
Chicago 17th Edition
Huljev Šipoš, Ivana, Slavica Labor, Iva Jurić, Davor Plavec, Kristian Vlahoviček, Siniša Bogović, Justinija Pavkov Vukelić i Marina Labor. "Dynamics of exhaled breath temperature after smoking a cigarette and its association with lung function changes predictive of COPD risk in smokers: a cross-sectional study." Arhiv za higijenu rada i toksikologiju 70, br. 2 (2019): 123-129. https://doi.org/10.2478/aiht-2019-70-3211
Harvard
Huljev Šipoš, I., et al. (2019). 'Dynamics of exhaled breath temperature after smoking a cigarette and its association with lung function changes predictive of COPD risk in smokers: a cross-sectional study', Arhiv za higijenu rada i toksikologiju, 70(2), str. 123-129. https://doi.org/10.2478/aiht-2019-70-3211
Vancouver
Huljev Šipoš I, Labor S, Jurić I, Plavec D, Vlahoviček K, Bogović S i sur. Dynamics of exhaled breath temperature after smoking a cigarette and its association with lung function changes predictive of COPD risk in smokers: a cross-sectional study. Arh Hig Rada Toksikol. [Internet]. 2019 [pristupljeno 06.12.2020.];70(2):123-129. https://doi.org/10.2478/aiht-2019-70-3211
IEEE
I. Huljev Šipoš, et al., "Dynamics of exhaled breath temperature after smoking a cigarette and its association with lung function changes predictive of COPD risk in smokers: a cross-sectional study", Arhiv za higijenu rada i toksikologiju, vol.70, br. 2, str. 123-129, 2019. [Online]. https://doi.org/10.2478/aiht-2019-70-3211

Sažetak
Exhaled breath temperature (EBT) is a biomarker of inflammation and vascularity of the airways already shown to predict incident COPD. This cross-sectional study was aimed to assess the potential of EBT in identifying “healthy” smokers susceptible to cigarette smoke toxicity of the airways and to the risk of developing COPD by analysing the dynamics of EBT after smoking a cigarette and its associations with their demographics (age, smoking burden) and lung function. The study included 55 current smokers of both sexes, 29–62 years of age, with median smoking exposure of 15 (10–71.8) pack-years. EBT was measured at baseline and 5, 15, 30, 45, and 60 min after smoking a single cigarette. Lung function was measured with spirometry followed by a bronchodilator test. To compare changes in EBT between repeated measurements we used the analysis of variance and the area under the curve (EBTAUC) as a dependent variable. Multivariate regression analysis was used to look for associations with patient characteristics and lung function in particular. The average (±SD) baseline EBT was 33.42±1.50 °C. The highest significant increase to 33.84 (1.25) °C was recorded 5 min after the cigarette was smoked (p=0.003), and it took one hour for it to return to the baseline. EBTAUC showed significant repeatability (ICC=0.85, p<0.001) and was significantly associated with age, body mass index, number of cigarettes smoked a day, baseline EBT, and baseline FEF75 (R2=0.39, p<0.001 for the model). Our results suggest that EBT after smoking a single cigarette could be used as early risk predictor of changes associated with chronic cigarette smoke exposure.

Ključne riječi
EBT; cigarette smoking; COPD risk; small airway dysfunction; cigarette smoke toxicity

Hrčak ID: 220946

URI
https://hrcak.srce.hr/220946

[hrvatski]

Posjeta: 455 *