Acta clinica Croatica, Vol. 58. No. 3., 2019.
Izvorni znanstveni članak
https://doi.org/10.20471/acc.2019.58.03.09
Twenty-Year Experience with Large Loop Excision of the Transformation Zone at Sestre Milosrdnice University Hospital Centre
Dražan Butorac
; Department of Obstetrics and Gynecology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Bernarda Škrtić
; Department of Obstetrics and Gynecology, Karlovac General Hospital, Karlovac, Croatia
Marijo Čukelj
; Department of Obstetrics and Gynecology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Krunoslav Kuna
; Department of Obstetrics and Gynecology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Ivka Djaković
orcid.org/0000-0003-2275-6389
; Department of Obstetrics and Gynecology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Sažetak
The 20-year experience with large loop excision of the transformation zone (LLETZ) at Gynecologic On-cology Unit, Department of Gynecology and Obstetrics, Sestre milosrdnice University Hospital Centre from Zagreb is presented. This retrospective observational study included 1407 women with cervical dys-plasia treated by LLETZ technique during the 1995-2016 period. LLETZ was most commonly performed in the 25-35 age group (51%), followed by the 36-45 age group (22%), and least frequently in the >65 age group (2%). Histopathologic results lower than high-grade squamous intraepithelial lesion were found in 23% and high grade squamous intraepithelial lesion or worse findings in 77% of patients. Positive margin as a sign of possible residual dysplasia was found in 25% of cones, 80% of which included endocervical positive margin. Cervical canal biopsy result was positive in 18% of cases. Accurate colposcopy and its findings can help avoid overtreatment, the rate of which was higher than expected in our retrospective study. Long-term follow up is an imperative for proper assessment of the procedure success. This method is the best choice for complete disease removal without unnecessary overtreatment, but it requires contin-uous education and training of the whole team.
Ključne riječi
Conization; Cervical intraepithelial neoplasia; Uterine cervical dysplasia; Colposcopy; Croa-tia
Hrčak ID:
230178
URI
Datum izdavanja:
1.9.2019.
Posjeta: 1.840 *