Acta clinica Croatica, Vol. 59. No. 2., 2020.
Pregledni rad
https://doi.org/10.20471/acc.2020.59.02.17
Myxopapillary Ependymoma of the Spinal Cord in Adults: a Report of Personal Series and Review of Literature
Ibrahim Omerhodžić
orcid.org/0000-0001-5143-8801
; Department of Neurosurgery, Sarajevo University Clinical Center, Sarajevo, Bosnia and Herzegovina
Mirza Pojskić
; Department of Neurosurgery, University of Marburg, Marburg, Germany; Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, Osijek, Croatia
Krešimir Rotim
; Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, Osijek, Croatia; University of Applied Health Sciences, Zagreb, Croatia; Department of Neurosurgery, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Bruno Splavski
orcid.org/0000-0002-4483-9364
; Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, Osijek, Croatia; University of Applied Health Sciences, Zagreb, Croatia; Department of Neurosurgery, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; Josip Juraj Strossmayer University of Osijek, School of Dental Medicine and Health, Osijek, Croatia
Lukas Rasulić
orcid.org/0000-0002-5674-0425
; Department of Neurosurgery, Clinical Center of Serbia, Belgrade, Serbia
Kenan I. Arnautovic
orcid.org/0000-0003-3745-288X
; Semmes Murphey Neurologic & Spine Institute, Memphis, TN, United States; Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, TN, United States
Sažetak
Myxopapillary ependymomas (MPE) of the spinal cord are slow-growing benign tumors most frequently found in adults between 30 and 50 years of age. They arise from the ependyma of the filum terminale and are located in the area of the medullary conus and cauda. The recommended treatment option is gross total resection, while patients undergoing subtotal resection usually require radiotherapy. Complete resection without capsular violation can be curative and is often accomplished by simple resection of the filum above and below the tumor mass. Nevertheless, dissemination and distant treatment failure may occur in approximately 30% of the cases. In this paper, we propose an original MPE classification, which is based upon our personal series report concerned with tumor location and its correlation with the extent of resection. We also provide literature review, discussing surgical technique, tumor recurrence rate and dissemination, and adjuvant treatment. In conclusion, our findings suggest that MPE management based on the proposed 5-type tumor classification is favorable when total surgical resection is performed in carefully selected patients. Yet, further studies on a much broader model is obligatory to confirm this.
Ključne riječi
Myxopapillary ependymoma; Gross total resection; Surgical technique; Tumor classification
Hrčak ID:
243692
URI
Datum izdavanja:
1.6.2020.
Posjeta: 2.615 *