Pregledni rad
Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease
Nikola Barić
Puni tekst: engleski pdf 522 Kb
str. 42-54
preuzimanja: 348
citiraj
APA 6th Edition
Barić, N. (2020). Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease. Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, . (544 =52-53), 42-54. Preuzeto s https://hrcak.srce.hr/248881
MLA 8th Edition
Barić, Nikola. "Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease." Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, vol. ., br. 544 =52-53, 2020, str. 42-54. https://hrcak.srce.hr/248881. Citirano 19.11.2024.
Chicago 17th Edition
Barić, Nikola. "Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease." Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti ., br. 544 =52-53 (2020): 42-54. https://hrcak.srce.hr/248881
Harvard
Barić, N. (2020). 'Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease', Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, .(544 =52-53), str. 42-54. Preuzeto s: https://hrcak.srce.hr/248881 (Datum pristupa: 19.11.2024.)
Vancouver
Barić N. Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease. Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti [Internet]. 2020 [pristupljeno 19.11.2024.];.(544 =52-53):42-54. Dostupno na: https://hrcak.srce.hr/248881
IEEE
N. Barić, "Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease", Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, vol.., br. 544 =52-53, str. 42-54, 2020. [Online]. Dostupno na: https://hrcak.srce.hr/248881. [Citirano: 19.11.2024.]
Puni tekst: hrvatski pdf 522 Kb
str. 42-54
preuzimanja: 243
citiraj
APA 6th Edition
Barić, N. (2020). Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease. Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, . (544 =52-53), 42-54. Preuzeto s https://hrcak.srce.hr/248881
MLA 8th Edition
Barić, Nikola. "Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease." Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, vol. ., br. 544 =52-53, 2020, str. 42-54. https://hrcak.srce.hr/248881. Citirano 19.11.2024.
Chicago 17th Edition
Barić, Nikola. "Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease." Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti ., br. 544 =52-53 (2020): 42-54. https://hrcak.srce.hr/248881
Harvard
Barić, N. (2020). 'Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease', Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, .(544 =52-53), str. 42-54. Preuzeto s: https://hrcak.srce.hr/248881 (Datum pristupa: 19.11.2024.)
Vancouver
Barić N. Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease. Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti [Internet]. 2020 [pristupljeno 19.11.2024.];.(544 =52-53):42-54. Dostupno na: https://hrcak.srce.hr/248881
IEEE
N. Barić, "Pathophysiological reasons for the failure of the cerebral perivascular drainage and progression of Alzheimer’s disease", Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, vol.., br. 544 =52-53, str. 42-54, 2020. [Online]. Dostupno na: https://hrcak.srce.hr/248881. [Citirano: 19.11.2024.]
Sažetak
The disorder of intracerebral perivascular drainage of amyloid beta (Aβ), as well as the drainage of various waste products related to a number of permanent biochemical reactions and physiological processes, leads to brain homeostasis disorders, breakdown of essential vital functions and rapid course of genetically programmed Alzheimer’s disease. As the brain does not have its own standard glymphatic system, this important function is mostly taken over by the perivascular system located within the basement membranes of capillaries, arterioles and arteries. The crucial driving force of this drainage, according to recent investigations, is conditioned by the internal force of arterial and arteriolar walls, the so-called vasomotion. With the direction opposite from the direction of the blood stream and pulse wave, this pulsating force is based on rhythmic intracellular oscillations of Ca2+ ion concentration in vascular smooth muscle cells. These oscilations are the fundament of the vasomotion phenomenon, and their disorder leads to perivascular drainage alterations and severe complications. The aim of this review is to present a detailed analysis of crucial events that are important for perivascular drainage system alterations.
Ključne riječi
Alzheimer’s disease, perivascular drainage alterations, glymphatic system, vasomotion phenomenon
Hrčak ID:
248881
URI
https://hrcak.srce.hr/248881
Datum izdavanja:
15.12.2020.
Podaci na drugim jezicima:
hrvatski
Posjeta: 1.496
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