Original scientific paper
https://doi.org/10.5599/jese.1141
Electrochemical determination of tramadol using modified screen-printed electrode
Sayed Zia Mohammadi
; Department of Chemistry, Payame Noor University, Tehran, Iran
Maedeh Jafari
; Department of Pediatrics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
Peyman Mohammadzadeh Jahani
; Student Research Committee, School of Public Health, Bam University of Medical Sciences, Bam, Iran
Sayed Ali Ahmadi
; Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran
Raana Mashayekh
; Student Research Committee, Bam University of Medical Sciences, Bam, Iran
Abstract
The detection of tramadol using a screen-printed electrode (SPE) modified with La3+/ZnO nano-flowers and multi-walled carbon nanotubes (La3+/ZnO NFs-MWCNTs/SPE) is reported in this work. To examine electrochemical oxidation of tramadol, the modified electrode was implemented with the utilization of differential pulse voltammetry, chronoamperometry and cyclic voltammetry as diagnostic techniques. The proposed electrode displays favorable electrocatalytic behavior concerning tramadol oxidation with an approximately 330 mV potential shift to less positive potential. In the range of tramadol concentrations of 0.5 to 800.0 μM, differential pulse voltammetry displays the linear response. Tramadol detection limit of 0.08 μM was achievedwithin optimized testing conditions for this sensorof simple construction. Lastly, thefabricated sensor was utilized for the determination oftramadol in urine samples.
Keywords
La3+/ZnO nano-flower; multi-walled carbon nanotubes; voltammetry
Hrčak ID:
273102
URI
Publication date:
24.2.2022.
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