Izvorni znanstveni članak
https://doi.org/10.15644/asc56/2/2
Dental Status and Periodontal Health of Patients with Phenylketonuria in Latvia
Iveta Abola
orcid.org/0000-0002-4569-7660
; Znanstveni laboratorij za molekularnu genetiku, Sveučilište Riga Stradiņš, Rīga, Latvija; Zavod za konzervativnu stomatologijui oralno zdravlje, Sveučilište Riga Stradiņš, Rīga, Latvija
*
Darta Elizabete Emulina
; Znanstveni laboratorij za molekularnu genetiku, Sveučilište Riga Stradiņš, Rīga, Latvija
Ingus Skadins
orcid.org/0000-0003-4044-8750
; Znanstveni laboratorij za molekularnu genetiku, Sveučilište Riga Stradiņš, Rīga, Latvija
Anda Brinkmane
; Zavod za konzervativnu stomatologijui oralno zdravlje, Sveučilište Riga Stradiņš, Rīga, Latvija
Linda Gailite
orcid.org/0000-0002-7219-1294
; Znanstveni laboratorij za molekularnu genetiku, Sveučilište Riga Stradiņš, Rīga, Latvija
Madara Auzenbaha
orcid.org/0000-0002-9925-2376
; Znanstveni laboratorij za molekularnu genetiku, Sveučilište Riga Stradiņš, Rīga, Latvija; Dječja klinička sveučilišna bolnica, Rīga, Latvija
* Dopisni autor.
Sažetak
Objectives: Phenylketonuria (PKU) is an autosomal recessive inherited disorder of phenylalanine metabolism resulting from a deficiency of phenylalanine hydroxylase. The aim of this study was to evaluate the dental status and periodontal health of PKU patients in Latvia. Material and Methods: Fortyfive PKU patients and age/sex-matched controls were recruited for this cross-sectional study. Their anamnestic data, periodontal health and dental status were assessed by one experienced dentist. Results: Dental and periodontal clinical evaluation revealed that the median number of filled teeth was significantly smaller among PKU patients compared to the control group (p=0.021). PKU patients had a significantly larger median number of carious teeth than their healthy counterparts (p<0.001). Significant differences between the PKU and control groups were observed for several oral hygiene indices (p<0.001): Silness-Löe plaque index, OR=29.3 (95% CI: 3.7–232.4); CPITN index, OR=35.2 (95% CI: 4.5–278.3); Greene-Vermillion index, OR=10.2 (95% CI: 2.8–38.0); calculus removal necessity, OR=12.3 (95% CI: 3.3–45.4). Conclusion: Dental status and periodontal health of PKU patients was found to be significantly inferior compared to healthy controls. This is likely due to the regular consumption of PKU formula and the difficulties which mentally and/or physically disabled PKU patients experience with their oral hygiene. To prevent tooth decay and periodontal disease, PKU patients should visit a professional oral hygienist every three to six months. Furthermore, they should adopt the habit of rinsing their mouth with water immediately after consuming PKU formula to counteract the acidity in their oral cavity.
Ključne riječi
Phenylketonuria; Oral Health; Periodontitis
Hrčak ID:
278932
URI
Datum izdavanja:
13.6.2022.
Posjeta: 1.847 *