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Libri Oncologici : Croatian Journal of Oncology, Vol. 50 No. 2-3, 2022.

Pregledni rad

https://doi.org/10.20471/LO.2022.50.02-03.19

Local treatment of breast cancer brain metastases

Ana Magličić orcid id orcid.org/0009-0006-4795-9157 ; Department of Gynecologic Oncology, University Hospital Center Zagreb, Zagreb, Croatia
Paula Podolski ; Department of Oncology, University Hospital Centre Zagreb, Zagreb, Croatia
Nera Šarić orcid id orcid.org/0009-0007-2904-1470 ; Department of Oncology, University Hospital Centre Zagreb, Zagreb, Croatia
Majana Soče ; Department of Oncology, University Hospital Centre Zagreb, Zagreb, Croatia
Maja Baučić orcid id orcid.org/0009-0009-4062-5834 ; Department of Oncology, University Hospital Centre Zagreb, Zagreb, Croatia
Sanja Vušković ; Department of Oncology, University Hospital Centre Zagreb, Zagreb, Croatia
Tena Mlinarić-Koprivanac ; Department of Gynecologic Oncology, University Hospital Center Zagreb, Zagreb, Croatia
Dora Šimović ; Department of Oncology, University Hospital Centre Zagreb, Zagreb, Croatia
Petra Đelalija orcid id orcid.org/0009-0002-9248-4972 ; Department of Oncology, University Hospital Centre Zagreb, Zagreb, Croatia
Ivan Zrilić ; General Hospital Zadar, Zadar, Croatia
Martina Bašić-Koretić ; Department of Oncology, University Hospital Centre Zagreb, Zagreb, Croatia

Puni tekst: engleski pdf 1.796 Kb

str. 126-130

preuzimanja: 358

citiraj

Sažetak

Breast cancer, along with lung cancer and melanoma, is one of the most common origins of central nervous system metastases. Due to improvement of systemic therapy options for primary disease and consequential prolonged survival, treatment of brain metastasis (BM) is presenting an evolving challenge. While new systemic therapy approaches for breast cancer brain metastasis are focusing on overcoming the blood brain and blood tumor barrier, as well as targeted therapies, local therapy remains the primary line of treatment. The decision of which local therapies to use, depends upon the number and volume of BM, their localization, patient’s clinical status, previously used treatments, status of extracranial disease and patient’s prognosis. In cases when an active approach, including surgery and/or radiotherapy, does not bring benefit to the patient’s quality of life or overall survival, best supportive care is recommended.

Ključne riječi

brain metastases; breast cancer; stereotactic radiosurgery; whole brain radiation therapy

Hrčak ID:

288540

URI

https://hrcak.srce.hr/288540

Datum izdavanja:

22.12.2022.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.554 *