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https://doi.org/10.15255/KUI.2023.005

Ru(III) Complexes and Their Ligands Derived from Salicylaldehyde and Halogenated Anilines: Synthesis, Characterisation, and Antioxidant Activity

Nevzeta Ljubijankić orcid.org/0000-0002-7421-4592 ; Sveučilište u Sarajevu, Prirodoslovno-matematički fakultet, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosna i Hercegovina
Enis Šuta orcid.org/0000-0002-2561-3001 ; Sveučilište u Sarajevu, Prirodoslovno-matematički fakultet, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosna i Hercegovina
Anela Ćatić ; Sveučilište u Sarajevu, Prirodoslovno-matematički fakultet, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosna i Hercegovina
Sabina Begić orcid.org/0000-0002-3523-8268 ; Sveučilište u Sarajevu, Prirodoslovno-matematički fakultet, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosna i Hercegovina
Sead Ljubijankić orcid.org/0000-0002-7421-4592 ; Sveučilište u Bihaću, Fakultet zdravstvenih studija, Nositelja hrvatskog trolista 4, Bihać, Bosna i Hercegovina
Saida Ibragić orcid.org/0000-0002-0201-4057 ; Sveučilište u Sarajevu, Prirodoslovno-matematički fakultet, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosna i Hercegovina

Sažetak

This work aimed to describe the synthesis and characterisation of two anionic Ru(III) complexes of the general formula Na[RuCl₂(N-4-Cl-Ph-salim)₂] and Na[RuCl₂(N-3-Br-Ph-salim)₂, their associated ligands, and determine their antioxidant activity. The ligands N-4-Cl-phenylsalicylidenimine (N-4-Cl-Ph-salimH, HLa) and N-3-Br-phenylsalicylidenimine (N-3-Br-Ph-salimH, HLb), Schiff bases, were synthesised from salicylaldehyde and chloroaniline or bromoaniline. The compounds were characterised using IR spectroscopy and ESI ToF mass spectrometry. The following was confirmed: coordination of ligands on the Ru(III) centre, the molecular formulas, and the corresponding M– ions: [C₂₆H₁₈N₂O₂Cl₄Ru]–26H₁₈N₂O₂Cl₂Br₂Ru]– ion, (m/z: 719.8283). The antioxidant activity was determined by the ABTS (2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and DPPH (1,1-diphenyl-2-picrylhydrazyl) assays. In contrast to the ligands, both complexes proved to be strong scavengers of the ABTS and DPPH radicals with IC₅₀ (half maximal inhibitory concentration) values comparable to those of Trolox. As such, they present valuable candidates for further research related to their biological properties.

Ključne riječi

Ru(III) complexes; Schiff bases; IR spectroscopy; ESI ToF mass spectrometry; antioxidant activity

Hrčak ID:

304923

URI

https://hrcak.srce.hr/304923

Datum izdavanja:

13.7.2023.

Podaci na drugim jezicima: hrvatski

Posjeta: 762 *