Izvorni znanstveni članak
https://doi.org/10.15255/KUI.2023.005
Ru(III) Complexes and Their Ligands Derived from Salicylaldehyde and Halogenated Anilines: Synthesis, Characterisation, and Antioxidant Activity
Nevzeta Ljubijankić
orcid.org/0000-0002-7421-4592
; Sveučilište u Sarajevu, Prirodoslovno-matematički fakultet, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosna i Hercegovina
Enis Šuta
orcid.org/0000-0002-2561-3001
; Sveučilište u Sarajevu, Prirodoslovno-matematički fakultet, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosna i Hercegovina
Anela Ćatić
; Sveučilište u Sarajevu, Prirodoslovno-matematički fakultet, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosna i Hercegovina
Sabina Begić
orcid.org/0000-0002-3523-8268
; Sveučilište u Sarajevu, Prirodoslovno-matematički fakultet, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosna i Hercegovina
Sead Ljubijankić
orcid.org/0000-0002-7421-4592
; Sveučilište u Bihaću, Fakultet zdravstvenih studija, Nositelja hrvatskog trolista 4, Bihać, Bosna i Hercegovina
Saida Ibragić
orcid.org/0000-0002-0201-4057
; Sveučilište u Sarajevu, Prirodoslovno-matematički fakultet, Zmaja od Bosne 33-35, 71 000 Sarajevo, Bosna i Hercegovina
Sažetak
This work aimed to describe the synthesis and characterisation of two anionic Ru(III) complexes of the general formula Na[RuCl2(N-4-Cl-Ph-salim)2] and Na[RuCl2(N-3-Br-Ph-salim)2, their associated ligands, and determine their antioxidant activity. The ligands N-4-Cl-phenylsalicylidenimine (N-4-Cl-Ph-salimH, HLa) and N-3-Br-phenylsalicylidenimine (N-3-Br-Ph-salimH, HLb), Schiff bases, were synthesised from salicylaldehyde and chloroaniline or bromoaniline. The compounds were characterised using IR spectroscopy and ESI ToF mass spectrometry. The following was confirmed: coordination of ligands on the Ru(III) centre, the molecular formulas, and the corresponding M– ions: [C26H18N2O2Cl4Ru]–26H18N2O2Cl2Br2Ru]– ion, (m/z: 719.8283). The antioxidant activity was determined by the ABTS (2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and DPPH (1,1-diphenyl-2-picrylhydrazyl) assays. In contrast to the ligands, both complexes proved to be strong scavengers of the ABTS and DPPH radicals with IC50 (half maximal inhibitory concentration) values comparable to those of Trolox. As such, they present valuable candidates for further research related to their biological properties.
Ključne riječi
Ru(III) complexes; Schiff bases; IR spectroscopy; ESI ToF mass spectrometry; antioxidant activity
Hrčak ID:
304923
URI
Datum izdavanja:
13.7.2023.
Posjeta: 325 *