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Agriculturae Conspectus Scientificus, Vol. 90 No. 2, 2025.

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Unlocking the Healing Power: Antioxidant, Anti-inflammatory, and Antibacterial Potentials of Pavetta siamica Bremek Leaves

Shamuntheswary Arumugam ; Chemical Sciences Programme, School of Distance Education, Universiti Sains Malaysia, Penang, Malaysia
Nurul Syafiqah Rezali orcid id orcid.org/0000-0002-4966-4233 ; Chemical Sciences Programme, School of Distance Education, Universiti Sains Malaysia, Penang, Malaysia
Zunoliza Abdullah ; Natural Products Division, Forest Research Institute Malaysia, Selangor, Malaysia
Mazura Md Pisar orcid id orcid.org/0000-0002-6876-1741 ; Natural Products Division, Forest Research Institute Malaysia, Selangor, Malaysia
Wan Mohd Nuzul Hakimi Wan Salleh orcid id orcid.org/0000-0003-1408-229X ; Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, Perak, Malaysia

Puni tekst: engleski pdf 520 Kb

str. 159-164

preuzimanja: 146

citiraj

Sažetak

The aim of the present study was to evaluate the antioxidant, anti-inflammatory and antibacterial activities of Pavetta siamica Bremek leaves from the Rubiaceae family. The study also aimed to identify the phytochemical components responsible for these bioactivities. The result revealed that n-hexane extract showed variable activity against all tested bacteria which are Staphylococcus aureus (14.7 ± 0.4 mm), Enterobacter aerogenes (9.0 ± 1.0 mm), Enterococcus faecalis (10.0 ± 1.0 mm) and Pseudomonas aeruginosa (8.3 ± 0.4 mm). The antioxidant activity of all extracts showed significant differences between less polar and more polar extracts with total phenolic content calculated as gallic acid equivalents (mg·L-1), ranged from 704 ± 38.0 to 12480 ± 75.3 mg, whereas the radical scavenging activity was evaluated at 517 nm with a value ranging between 3.71% ± 0.13 to 90.11% ± 0.05. On the other hand, the anti-inflammatory activity of less polar extracts showed 100% inhibition at a constant dosage of 500 μg'mL-1 in both anti-denaturation and anti-hyaluronidase assays. Phytochemical screening of extracts revealed the presence of flavonoids, phenols and tannins in both methanol and aqueous extracts while glycosides, terpenoids and steroids were found in less polar extracts.

Ključne riječi

Pavetta siamica Bremek, Rubiaceae; antioxidant, anti-inflammatory, antibacterial

Hrčak ID:

333059

URI

https://hrcak.srce.hr/333059

Datum izdavanja:

6.6.2026.

Posjeta: 344 *